产品说明
DescriptionCatalogueNumberAB9272Replaces04-1019BrandFamilyChemicon®TradeNameChemiconDescriptionAnti-SynaptophysinAntibodyProductInformationFormatAffinityPurifiedControlPOSITIVECONTROL:PancreasorPheochromocytomaPresentationAffinitypurifiedimmunoglobulin.Liquidin10mMPBS,pH7.4containingBSAand0.1%sodiumazide.StorageandShippingInformationStorageConditionsMaintainat2-8°Cforupto6monthsafterdateofreceipt.ApplicationsApplicationAnti-SynaptophysinAntibodydetectslevelofSynaptophysin&hasbeenpublished&validatedforuseinWB,IH(P).KeyApplicationsWesternBlottingImmunohistochemistry(Paraffin)ApplicationNotesWesternblotImmunohistochemistryonformalinfixed,paraffinembeddedtissue:1:300for10minutesatroomtemperature.Stainingofformalin-fixedtissuesrequiresboilingoftissuesin10mMcitratebuffer,pH6.0for10minutesfollowedbycoolingatroomtemperaturefor20minutes.Optimalworkingdilutionsmustbedeterminedbytheenduser.STAININGPATTERN:CytoplasmicBIOLOGicalInformationImmunogenSyntheticpeptidefromhumansynaptophysin.HostRabbitSpecificitySynaptophysinSpeciesReactivityHumanRatAntibodyTypePolyclonalAntibodyEntrezGeneNumberNM_003179.2EntrezGeneSummarySynaptophysin(p38)isanintegralmembraneproteinofsmallsynapticvesiclesinbrainandendocrinecells.[suppliedbyOMIM]GeneSymbolSYPsynaptophysinSynaptophysinUniProtNumberP08247UniProtSummaryFUNCTION:SwissProt:P08247#PossIBLyinvolvedinstructuralfunctionsasorganizingothermembranecomponentsorintargetingthevesiclestotheplasmamembrane.SIZE:313aminoacids;33845DaSUBUNIT:Homohexamerorhomotetramer.SUBCELLULARLOCATION:Cytoplasmicvesicle,secretoryvesicle,synapticvesiclemembrane;Multi-passmembraneprotein.TISSUESPECIFICITY:Characteristicofatypeofsmall(30-80nm)neurosecretoryvesicles,includingpresynapticvesicles,butalsovesiclesofvariousneuroendocrinecellsofbothneuronalandepithelialphenotype.DOMAIN:SwissProt:P08247Thecalcium-bindingactivityisthoughttobelocalizedinthecytoplasmictailoftheprotein.PTM:Ubiquitinated;mediatedbySIAH1orSIAH2andleADIngtoitssubsequentproteasomaldegradation(Bysimilarity).SIMILARITY:Belongstothesynaptophysin/synaptobrevinfamily.&Contains1MARVELdomain.PhysicochemicalInformationDimensionsMaterialsInformationMaterialsInformation
密理博(Millipore)公司成立于1954年,总部位于美国麻省,在全世界设有47个办事处,为100多个国家提供产品和技术服务。目前全球雇员超过5800人,在美国、法国和日本等国家拥有7家大型生产工厂,主要生产过滤膜及膜过滤产品。
20世纪80年代,密理博公司进入中国市场。先后在香港、北京、上海、广州及成都设立了办事机构,并于2000年4月在上海浦东外高桥保税区建立了密理博(上海)贸易有限公司。
为了更好地满足中国用户的需求,密理博中国主页于2006年11月向广大用户开放,介绍密理博中国有限公司的最新动态,力求为用户打造专业的产品与服务信息交流平台。
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