首页 > Millipore > Millipore/07-442-AF488 | Anti-trimethyl Histone H3 (Lys9) Antibody, Alexa Fluor® 488 Conjugate/07-442-AF488/100 µL

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Millipore/07-442-AF488 | Anti-trimethyl Histone H3 (Lys9) Antibody, Alexa Fluor® 488 Conjugate/07-442-AF488/100 µL

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Description Catalogue Number07-442-AF488 DescriptionAnti-trimethyl Histone H3 (Lys9) Antibody, Alexa Fluor® 488 Conjugate Alternate NamesHistone H3.1tH3/tH3tH3/g Background InformationHistone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. Histone proteins are highly post-translationally modified, and Histone H3 is the most extensively modified of the five histones. Histone H3 sequence variants and variable modification states are thought to play a role in the dynamic and long term regulation of genes. Di- and tri-methylation of histone H3 are gene silencing marks, while removal of these marks by the demethylase genes Jmjd1a and Jmjd2c leads to gene activation. This product is a conjugated version of Cat. No. 07-442. Product Information FormatAlexaFluor®488 PresentationPurified rabbit conjugate in buffer containing PBS with 15 mg/ml BSA and 0.1% Sodium Azide. Storage and Shipping Information Storage ConditionsStable for 1 year at 2-8°C from date of receipt. Applications ApplicationThis Anti-trimethyl Histone H3 (Lys9) Antibody, Alexa Fluor® 488 Conjugate is validated for use in ICC for the detection of trimethyl Histone H3 (Lys9). Key ApplicationsImmunocytochemistry Biological Information ImmunogenLinear peptide corresponding to Histone H3 trimethylated at Lys9. Concentration0.5 mg/mL HostRabbit Species ReactivityHuman Species Reactivity NoteHuman. Predicted to react with Mouse, Rat, and Chicken based on 100% sequence homology. Antibody TypePolyclonal Antibody Entrez Gene NumberNM_003493 Gene SymbolHIST3H3H3FT Purification MethodProtein A Purfied UniProt NumberQ16695 Molecular Weight~17 kDa observed (Refer to Cat. No. 07-442) Physicochemical Information Dimensions Materials Information Materials Information

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