首页 > Epigentek > Epigentek/APOBEC3A Polyclonal Antibody/A58106-100/100 µg

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Epigentek/APOBEC3A Polyclonal Antibody/A58106-100/100 µg

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A58106-100

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Application: ELISA Areas of Research: DNA Methylation Clonality: Polyclonal Conjugate: Unconjugated Host: Rabbit Isotype: IgG Purification: >95%, Protein G Purified Reactivity: Human 100% Guarantee: 6 months Product Overview BackgroundDNA deaminase (cytidine deaminase) with restriction activity against viruses, foreign DNA and mobility of retrotransposons. Exhibits antiviral activity against adeno-associated virus (AAV) and human T-cell leukemia virus type 1 (HTLV-1) and may inhibit the mobility of LTR and non-LTR retrotransposons. Selectively targets single-stranded DNA and can deaminate both methylcytosine and cytosine in foreign DNA. Can induce somatic hypermutation in the nuclear and mitochondrial DNA. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation. DescriptionAPOBEC3A Polyclonal Antibody. Unconjugated. Raised in: Rabbit. FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4. SpecificityHuman IsotypeIgG Uniprot IDP31941 Purification>95%, Protein G purified ImmunogenRecombinant human DNA dC->dU-editing enzyme APOBEC-3A protein (1-199AA) StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze. Alternative NamesDNA dC->dU-editing enzyme APOBEC-3A (EC:3.5.4.-), A3A, APOBEC3A, Phorbolin-1 ApplicationELISA VCU0006

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