MembersofthegenusChlamydiaareobligateintracellulargram-negativebacteriathatbelongtothefamilyChlamydiaceae.ThreespeciesofChlamydiaareknowntobepathogenictohumansincludingChlamydiatrachomatis(C.trachomatis),Chlamydiapneumonia(C.pneumonia)andChlamydiapsittaci(C.psittaci).Chlamydiatrachomatisstrainsaredividedintothreebiovars,whicharefurtherdividedintofifteenSEROvarsA,B,Ba,serovarsC-KandserovarsL1-L3.ChlamydiatrachomatisserovarsA-Ccauseeyeinfectionsknownastrachoma.SerovarsD-KareresponsIBLeforbacterialsexuallytransmittedgenitaltractinfectionsinwomenandmen.ChlamydiatrachomatisserovarsL1,L2andL3areresponsibleforaconditionknownasLymphogranulomavenereum(LGV)(Elwell,C).Inwomen,C.trachomatisinfectsthecervixwhichmayleadtocervicitis.However,70-80%ofwomenwithC.trachomatisgenitaltractinfectionremainasymptomatic.In10%ofcases,thebacteriumcaninfecttheuppergenitaltractleADIngtopelvicinflammatorydisease,scarringoftheFallopiantubes,ectopicpregnanciesandinfertility.C.trachomatiscanalsobetransmittedtobABIesborntoinfecteduntreatedmothersduringchildbirth,causingconjunctivitisorpneumonia.C.pneumoniainfectsthelungscausingatypeofatypicalpneumonia.Thebacteriacanbespreadviaairbornedropletsfrompersontopersonandthroughclosecontactwithinfectedindividuals.Primaryinfectiontypicallyoccursinchildren,butre-infectioncanoccurlaterinadultlife(CDC).C.psittaciinfectionprimarilyaffectsbirdssuchasparrots,parakeets,dovesandpigeonscausingthediseasepsittacosis.C.psittacicanbetransmittedtohumansthatcomeintoclosecontactwithbirdsthroughexposuretobirdfecesandinhalationofrespiratoryparticlesfrominfectedbirds.Inhumans,C.psittaciinfectioncausesanacuterespiratorydiseasewithflu-likesymptoms(GOV.UK).||Applications:|SuitableforuseinELISA.Otherapplicationsnottested.||RecommendedDilution:|Optimaldilutionstobedeterminedbytheresearcher.||StorageandStability:|Maybestoredat4°Cforshort-termonly.Aliquottoavoidrepeatedfreezingandthawing.Storeat-20°C.Aliquotsarestablefor12monthsafterreceipt.Formaximumrecoveryofproduct,centrifugetheoriginalvialafterthawingandpriortoremovingthecap.ProductType:Mab|Isotype:IgG2b|CloneNo:1645|Host:Mouse|Concentration:~1mg/ml|Form:SuppliedasaliquidinPBS,pH7.2,0.09%sodiumazide.|Purity:PurifiedbyProteinAaffinitychromatography.|Specificity:Recognizeslipopolysaccharide(LPS)frommembersofthegenus|Chlamydia,andrecognizesLPSfromC.trachomatis,C.pneumoniaeandC.psittaci.||ImportantNote:Thisproductassuppliedisintendedforresearchuseonly,notforuseinhuman,therapeuticordiagnosticapplicationswithouttheexpressedwrittenauthorizationofUnitedStatesBIOLOGical.

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