首页 > BPS Bioscience > Bpsbioscience/Anti-PD-1 Neutralizing Antibody/71120/100 µg

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Bpsbioscience/Anti-PD-1 Neutralizing Antibody/71120/100 µg

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71120

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Species:Human/MouseHostSpecies:Freestyle293cellsMW:50and25kDafortheheavyandlightchains,respectively(150kDa).Tag(s):noneClonality:MonoclonalIsotype:IgG1Description:Neutralizingrecombinantmurine/humanchimericantibodyrecognizingthePD-L1/PD-L2bindingregionofhumanPD-1.Thisantibodydoesnotcross-reactwithmousePD-1,butdoescross-reactwithmonkey(M.fascicularis)PD-1.Ithasnotbeentestedwithotherspecies.UniProtQ15116Synonym(s):Anti-PD1SpecificActivity:IC50=1.2nMusingthePD-1[Biotinylated]:PD-L1InhibitorScreeningAssayKit(BPSCat.#72005).IC50=4.7nMusingthePD-1[Biotinylated]:PD-L2InhibitorScreeningAssayKit(BPSCat.#72006).AssayConditions:AntibodywasaddedtoPD-1[Biotinylated]:PD-L1orPD-1[Biotinylated]:PD-L2bindingassayatvariousconcentrations.AssaywasperformedaccordingtotheprotocolinBPSCat.#72005or#72006,respectively.Formulation:40mMTris-HCl,pH8.0,110mMNaCl,2.2mMKCl,and20%glycerol.Purification:ProteinAaffinitychromatographyfromHEK293supernatants.Immunogen:PD-L1/L2bindingregionofhumanPD-1Format:AqueousbuffersolutionStorage/StABIlity:Stableforatleast12monthsat-80°C.Storedilutedantibodywithcarrierprotein(BSA0.1–0.5%)at4°C,stablefor2weeks.Application(s):UsefulasacontrolinhibitorofPD-1bindingusingthePD-1:PD-L1[Biotinylated]InhibitorScreeningAssayKit,BPSBioscience,Catalog#72003.Reference(s):1.Shinohara,T.,etal.,Genomics.1994Oct;23(3):704-6.2.James,E.S.,etal.,GenesImmun.2005Aug;6(5):430-7.Warning(s):Avoidfreeze/thawcycles.ScientificCategory:CellSurfaceReceptorProductType:AntibodyDatashownislot-specific.Contactusforspecificinformationonotherlots.

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