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StressMarq/Dovitinib/SIH-500-5MG/5-mg

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SIH-500-5MG

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Overview:ProductNameDovitinibDescriptionFGFR3inhibitorPurity>98%CASNo.405169-16-6MolecularFormulaC21H21FN6OMolecularWeight392.4PropertiesStorageTemperature-20ºCShippingTemperatureShippedAmbientProductTypeInhibitorSolubilitySolubleinDMSOSourceSyntheticAppearanceCrystallinesolidSMILESCN1CCN(CC1)C2=CC3=C(C=C2)N=C(N3)C4=C(C5=C(C=CC=C5F)NC4=O)NInChIInChI=1S/C21H21FN6O/c1-27-7-9-28(10-8-27)12-5-6-14-16(11-12)25-20(24-14)18-19(23)17-13(22)3-2-4-15(17)26-21(18)29/h2-6,11,24-25H,7-10,23H2,1H3/b20-18-InChIKeyKCOYQXZDFIIGCY-ZZEZOPTASA-NSafetyPhrasesClassification:SkinCorrosion/Irritation,Category2SeriousEyeDamage/EyeIrritation,Category2TargetOrganSystemicToxicity(singleexposure),Category3SafetyPhrases:S22-Donotbreathedust.S24/25-Avoidcontactwithskinandeyes.S36/37/39-Wearsuitableprotectiveclothing,glovesandeye/faceprotection.Hazardstatements:H315:Causesskinirritation.H319:Causesseriouseyeirritation.H335:Maycauserespiratoryirritation.Precautionarystatements:P302+352:IFONSKIN:Washwithplentyofsoapandwater.P332+313:Ifskinirritationoccurs,getmedicaladvice/attention.P305+351+338:IFINEYES:Rinsecautiouslywithwaterforseveralminutes.Removecontactlenses,ifpresentandeasytodo.Continuerinsing.P337+313:Ifeyeirritationpersists,getmedicaladvice/attention.P304+340:IFINHALED:Removevictimtofreshairandkeepatrestinapositioncomfortableforbreathing.P312:Calla{POISONCENTER/doctor/...}ifyoufeelunwell.CiteThisProductDovitinib(StressMarqBiosciencesInc.,VictoriaBCCANADA,Catalog#SIH-500)BIOLOGicalDescriptionAlternativeNames4-amino-5-fluoro-3-[6-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-2(1H)-quinolinoneResearchAreasCellSignalingPubChemID9886808ScientificBackgroundDovitinibisapotentgrowthfactorreceptorkinaseinhibitorwitheffectsagainstFLT-3,c-KIT,VEGFR,PDGFRßandCSF-1R.References1.KonecnyG.E.,etal.(2013)Mol.CancerTher.12(5):632–642.ProductImagesChemicalstructureofDovitinib(SIH-500),aFGFR3inhibitor.CAS#:405169-16-6.MolecularFormula:C21H21FN6O.MolecularWeight:392.4g/mol.ProductCitations(0)Currentlytherearenocitationsforthisproduct.

StressMarq Biosciences公司的核心技术领域为细胞应激与离子通道以及载体研究，同时在其他领域也取得了一定成就，包括翻译后修饰，提供甲基化与乙酰基化抗体。其中，细胞应激领域主要包括热休克蛋白（HSP）领域。我们公司不仅在热休克蛋白领域领先全球，而且在氧化应激领域也卓有成就。StressMarq的优势在于提供四种独立的产品系列，分别涉及抗体、蛋白、酶联免疫吸附试验（ELISA）试剂盒及小分子领域。