Product Code Product Name Goat anti Human high molecular weight kininogen (light chain specific) Size 1 ml Price (USD) $362 Background The defined antibody specificity is to human high molecular weight kininogen. In immunoelectrophoresis, bi-dimensional electrophoresis and radial immunodiffusion (Ouchterlony, Mancini), using various antiserum concentrations against normal plasma, one single precipitin line is obtained. No precipitation is observed against plasma of patients with high molecular weight kininogen deficiency, but its presence can be demonstrated in normal serum. In double radial immunodiffusion the precipitin line obtained against normal plasma shows a reaction of full identity with the precipitin line with purified high molecular weight kininogen. As precipitating antiserum in electroimmunodiffusion, immunoelectrophoresis and radial immunodiffusion. This does not exclude the use of the antiserum in more sensitive techniques if proper controls are included. Host Goat Species Reactivity Human Product Usage Precipitating polyclonal Goat antiSerum to Human high molecular weight kininogen Product Type Primary Antibodies Applications Immunoprecipitation Fields of Interest Extracellular matrix, Cardiovascular Product Source Highly purified molecular weight kininogen isolated from pooled plasma. Freund Product Formulation Delipidated, heat inactivated, lyophilized, stable whole serum. No preservative added. Total protein and IgG concentration in the antiserum are comparable to those of pooled normal goat serum. No foreign proteins added. Product Specificity The antiSerum does not cross-react with any other Human plasma proteins as tested in gel-diffusion techniques. Inter-species cross-reactivity is a normal feature of antibodies to plasma proteins, since homologous proteins of different species frequently share antigenic determinants. Cross-reactivity of this antiSerum has not been tested in detail, however in double radial immunodiffusion a reaction with Monkey has been observed. Storage Conditions The lyophilized antiserum is shipped at ambient temperature and may be stored at +4