首页 > NSJ Bio > NSJ Bio/Recombinant MMP9 Antibody / Rabbit Monoclonal [clone MMP9/2025R] (V3626)/100 ug/V3626SAF-100UG

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NSJ Bio/Recombinant MMP9 Antibody / Rabbit Monoclonal [clone MMP9/2025R] (V3626)/100 ug/V3626SAF-100UG

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V3626SAF-100UG

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NSJ Bio

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DescriptionThe matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP9 (also designated 92 kDa type IV collagenase or gelatinase B) has been shown to degrade bone collagens in concert with MMP1 (also designated interstitial collagenase, fibroblast collagenase or collagenase-1), and cysteine proteases and may play a role in bone osteoclastic resorption. MMP1 is down-regulated by p53, and abnormality of p53 expression may contribute to joint degradation in rheumatoid arthritis by regulating MMP1 expression.Application NotesOptimal dilution of the recombinant MMP9 antibody should be determined by the researcher.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.ImmunogenAmino acids 603-614 were used as the immunogen for the recombinant MMP9 antibody.StorageStore the recombinant MMP9 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).Related Products1. View all MMP9 antibodies2. View all recombinant antibodies

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