首页 > NSJ Bio > NSJ Bio/Dystrophin Antibody / DMD [clone DSTN-1] (V7555)/100 ug/V7555SAF-100UG

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NSJ Bio/Dystrophin Antibody / DMD [clone DSTN-1] (V7555)/100 ug/V7555SAF-100UG

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V7555SAF-100UG

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NSJ Bio

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DescriptionThe DMD gene spans a genomic range of greater than 2 Mb and encodes a large protein containing an N-terminal actin-binding domain and multiple spectrin repeats. The encoded protein forms a component of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extracellular matrix. Deletions, duplications, and point mutations at this gene locus may cause Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), or cardiomyopathy. Alternative promoter usage and alternative splicing result in numerous distinct transcript variants and protein isoforms for this gene. [RefSeq]Application NotesOptimal dilution of the Dystrophin antibody should be determined by the researcher.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.ImmunogenAmino acids 114-263 from the human protein were used as the immunogen for the Dystrophin antibody.StorageStore the Dystrophin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).Related Products1. View all Dystrophin antibodies

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