首页 > NSJ Bio > NSJ Bio/IL-1B Antibody [clone 614CT4.3.1] (F53698)/0.1 ml/F53698-0.1ML

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NSJ Bio/IL-1B Antibody [clone 614CT4.3.1] (F53698)/0.1 ml/F53698-0.1ML

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F53698-0.1ML

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NSJ Bio

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DescriptionThe protein encoded by this gene is a member of theinterleukin 1 cytokine family. This cytokine is produced byactivated macrophages as a proprotein, which is proteolyticallyprocessed to its active form by caspase 1 (CASP1/ICE). Thiscytokine is an important mediator of the inflammatory response, andis involved in a variety of cellular activities, including cellproliferation, differentiation, and apoptosis. The induction ofcyclooxygenase-2 (PTGS2/COX2) by this cytokine in the centralnervous system (CNS) is found to contribute to inflammatory painhypersensitivity. This gene and eight other interleukin 1 familygenes form a cytokine gene cluster on chromosome 2. [provided byRefSeq].Application NotesTitration of the IL-1B antibody may be required due to differences in protocols and secondary/substrate sensitivity.ImmunogenA portion of amino acids 148-174 from the human protein was used as the immunogen for this IL-1B antibody.StorageAliquot the IL-1B antibody and store frozen at -20oC or colder.Avoid repeated freeze-thaw cycles. Related Products1. View all IL-1B antibodies

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