产品说明
LNX1Catalogue number: X2341BProduct Type Blocking PeptideUnits50 µg HostRabbit Species reactivity HumanApplication Western Blotting BackgroundLNX1 is an E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NUMB. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65Synonyms: Numb-binding protein 1; Ligand of Numb-protein X 1 Source Immunogen: Synthetic peptide derived from the human LNX1 protein. Product Product Form: Unconjugated Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azideConcentration: See vial for concentration ApplicationsFor use with LNX1 polyclonal antibodies (Cat. No. X2316P & X2340P).Functional Analysis: Western BlottingPositive Control: Protein expressed in heart, placenta, kidney, pancreas and brain. StorageProduct should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles Product Stability: Products are stable for one year from purchase when stored properly Shipping Conditions: Ship at ambient temperature, freeze upon arrival CautionThis product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information. References1. Armbruester, V., et al. 'Np9 protein of human endogenous retrovirus K interacts with ligand of numb protein X.; J. Virol. 78:10310-10319(2004).2. Sollerbrant, K., et al. 'The Coxsackievirus and adenovirus receptor (CAR) forms a complex with the PDZ domain-containing protein ligand-of-numb protein-X (LNX).; J. Biol. Chem. 278:7439-7444(2003).3. Xie, Y., et al. 'Identification of a human LNX protein containing multiple PDZ domains.; Biochem. Genet. 39:117-126(2001).Protein Reference(s)Database Name: UniProt Accession number: Q8TBB1 Species Accession: Human Safety Datasheet(s) for this product:NM_Sodium Azide/wp-content/uploads/SDS/Antibody SDS with Sodium Azide Noridic-MUbio.pdf
Noridic-Mubio是荷兰的一家著名的免疫学试剂生产厂商,因收购An Der Grub Bio Research GmbH(ADG),增加了自己的产品线:全球最好的固定破膜剂FIX&PERM 。Nordic-Mubio严格遵照ISO9001标准生产高质量的抗体,主要为针对细胞粘附蛋白、核蛋白和骨架蛋白的抗体。同时Nordic-Mubio也是斑马鱼抗体开发的引领者之一,拥有50多种可用于斑马鱼免疫荧光检测的抗体。
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