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FabGennix/C6orf150 Antibody/CGAS-101AP
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DescriptionPublicationsbody { line-height:115%; font-family:Calibri; font-size:11pt }p { margin:0pt 0pt 10pt }table { margin-top:0pt; margin-bottom:10pt }.BalloonText { margin-bottom:0pt; line-height:normal; font-family:Tahoma; font-size:8pt }span.BalloonTextChar { font-family:Tahoma; font-size:8pt }span.Hyperlink { text-decoration:underline; color:#0000ff }.TableGrid { margin-bottom:0pt; line-height:normal }General InformationProductC6orf150 AntibodyDescriptionAffinity Purified Cyclic GMP-AMP synthase Antibody Verified ApplicationsELISA, IHC, IP, WBHostRabbitSpecies Cross ReactivityMouse, RatImmunogenSynthetic peptide taken within amino acid region 450-500 on mouse cGAS protein.Accession #NCBI: NP_775562Physical PropertiesQuantity100 µgVolume200 µlConcentration0.60 µg/µl in antibody stabilization bufferFormAffinity PurifiedClonalityPolyclonalStorage-20⁰C for long term storageApplication ProtocolDB1:10,000ELISA1:10,000Immunohistochemistry1:100Immunoprecipitation1:150Western Blot1:500ProteinUniprot #Q8C6L5OverviewCatalyzes the formation of cyclic GMP-AMP from ATP and GTP. Has antiviral activity through acting as a cystolic DNA senser.Molecular FunctionNucleotidyltransferase; ATP binding; DNA bindingSubcellular LocationCytoplasm; CytosolExpressionIs expressed in the monocytic cell line THP1 by type 1 InterferonsStructureMonomer when in absence of DNA. Homodimer when bound to DNA.Alternative NomenclatureC6orf150 antibodycGAMP synthase antibodycGAS antibodyChromosome 6 open reading frame 150 antibodyCyclic GMP-AMP synthase antibodyh-cGAS antibodyHypothetical protein LOC115004 antibodyMab 21 domain containing 1 antibodyMB21D1 antibodyprotein MB21D1 antibodyUncharacterized protein C6orf150 antibodyProtein information supplied by UniProtbody { line-height:115%; font-family:Calibri; font-size:11pt }p { margin:0pt 0pt 10pt }table { margin-top:0pt; margin-bottom:10pt }span.Hyperlink { text-decoration:underline; color:#0000ff }.TableGrid { margin-bottom:0pt; line-height:normal }Fabgennix cGAS Antibody has been used in 1 PublicationIijima, Kenta, Shigeyuki Kano, and Yukihito Ishizaka. “Viral protein R of human immunodeficiency virus type‐1 induces retrotransposition and upregulates glutamate synthesis by the signal transducer and activator of transcription 1 signaling pathway.“Microbiology and Immunology (2015).PMID25990091 Western Blot; MousePublishing research using CGAS-101AP? Please let us know, we can cite the reference in this datasheet.

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