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Aves Labs/Kv2.1 K+ channel (7x-014)/Purified Trial-Size (75-014-020)

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PurifiedTrial-Size(75-014-020)

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Volume: Purified: 100 µL; Purified Trial: 20 µL; TC Supernatant: 5 mLConcentration: Purified: 1 mg/mL; TC Supernatant: Lot SpecificClonality: MonoclonalForm: Purified and TC Supernatant Available (select your preferred form, size and quantity before clicking "Add to Cart")Host Species: MouseImmunogen: Synthetic peptide amino acids 837-853 (HMLPGGGAHGSTRDQSI, cytoplasmic Cterminus) of rat Kv2.1 (also known as Potassium voltage-gated channel subfamily B member 1, Delayed rectifier potassium channel 1, DRK1, Kcnb1 and Shab, accession number P15387)Mouse: 100% identity (17/17 amino acids identical)Human: 88% identity (15/17 amino acids identical, RVLPGGGAHGSTRDQSI)Target Description: Kv 2.1 K+ channel (Potassium voltage-gated channel subfamily B member 1), which is encoded by KCNB1 gene, is a member of the Potassium voltage-gated channel familly. This protein, mainly expressed in the central nervous system, functions as a delayed rectifier. Indeed, it regulates the action potential (AP) repolarization as well as duration and frequency of repetitive AP firing in neurons, muscle cells and endocrine cells. Kv2.1 K+ channel switches between open or closed conformation in response to the voltage difference across the membrane. This process directs the voltage-dependent potassium ion permeability of excitable membranes, which lets potassium ions pass in accordance with their electrochemical gradient. Kv2.1 K+ channel is widely used as a marker to measure membrane excitability in hippocampal neurons.Gene ID: Kcnb1Antibody Registry ID (RRID): AB_10673392Physical State: LiquidValidation and Application NotesMolecular Weight: 105-125 kDa(varies with cell background due to phosphorylation)NOTEAves Labs products are intended for use as research laboratory reagents. They are not intended for use as diagnostic or therapeutic reagents in humans.↑ back to top

神经元标志蛋白抗体

该系列产品主要用于神经元细胞的各亚细胞结构研究，可与现有的小鼠/兔抗体进行免疫双标，反应性包括人、小鼠等多个哺乳类动物。在保证抗体特异性的前提下，部分产品可分为抗不同的氨基酸片段。该系列产品包括抗APP3/APP345/APP4/APP5/ABN/TUJ/CAT/ DCX/ER1/ER2/ER3/ER5/GAD/GAP43/MAP/NET/ NUN/NSE/ NFH / NFL / NFM / PER/ PRN / PAP/ STG / TAU / TYH的抗体。除单独的抗体提供，我们还可同时提供1/3种任意抗体组合及相应二抗的试剂盒，以更优惠的价格及便捷性以满足研究人员的不同需要。