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Altogen/IN-VIVO TRANSFECTION KITS:/PANCREAS-targeted In Vivo Transfection Reagent - 1.5 ml – 30 injections/5051
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DescriptionNOTE: To place order using Credit Card, P-Card, or Purchase Order – please choose kit size above and click “Add to cart” button. You can place order online without creating an account.LIPID-based In Vivo Transfection Kit for Rodents (Mouse, Rat)Cationic lipid liposome-based siRNA and plasmid DNA in vivo delivery reagentEfficient delivery to the liver, pancreas, kidney, and certain tumor types via systemic administrationComplete product support information is available at: LIPID In Vivo Transfection KitFigure 1. Systemic administration (i.v.) of Lipid-based In Vivo reagent conjugated with siRNA targeting Lamin A/C mRNA or non-silencing control siRNA following the recommended protocol. Tissues were collected and RNA isolated 48 hours after first injection. Samples were analyzed by qRT-PCR for Lamin A/C gene expression levels. Ribosomal RNA levels were used to normalize the Lamin A/C data. Data are means ± SD (n=6).Figure 2. Intratumoral administration (i.t.) of Lipid-based In Vivo reagent conjugated with siRNA targeting Lamin A/C mRNA or non-silencing control siRNA following the recommended protocol. Tissues were collected and RNA isolated 48 hours after first injection. Samples were analyzed by qRT-PCR for Lamin A/C gene expression levels. Ribosomal RNA levels were used to normalize the Lamin A/C data. Data are means ± SD (n=6).POLYMER-based In Vivo Transfection Kit for Rodents (Mouse, Rat)Biodegradable polymer-based in vivo reagentEfficient delivery to the lung, liver, kidney, and spleen via systemic administrationComplete product support information is available at: POLYMER In Vivo Transfection KitFigure 3. Systemic administration (i.v.) of Polymer-based In Vivo reagent conjugated with siRNA targeting Lamin A/C mRNA or non-silencing control siRNA following the recommended protocol. Tissues were collected and RNA isolated 48 hours after first injection. Samples were analyzed by qRT-PCR for Lamin A/C gene expression levels. Ribosomal RNA levels were used to normalize the Lamin A/C data. Data are means ± SD (n=6).Figure 4. Intratumoral administration (i.t.) of Polymer-based In Vivo reagent conjugated with siRNA targeting Lamin A/C mRNA or non-silencing control siRNA following the recommended protocol. Tissues were collected and RNA isolated 48 hours after first injection. Samples were analyzed by qRT-PCR for Lamin A/C gene expression levels. Ribosomal RNA levels were used to normalize the Lamin A/C data. Data are means ± SD (n=6).NANOPARTICLE-based In Vivo Transfection Kit for Rodents (Mouse, Rat)Nanoparticle-based reagentEfficient delivery to the heart, lung, liver, pancreas, kidney, and multiple tumor types via systemic administrationComplete product support information is available at: NANOPARTICLE In Vivo Transfection KitFigure 5. Systemic administration (i.v.) of Nanoparticle-based In Vivo reagent conjugated with siRNA targeting Lamin A/C mRNA or non-silencing control siRNA following the recommended protocol. Tissues were collected and RNA isolated 48 hours after first injection. Samples were analyzed by qRT-PCR for Lamin A/C gene expression levels. Ribosomal RNA levels were used to normalize the Lamin A/C data. Data are means ± SD (n=6).Figure 6. Intratumoral administration (i.t.) of Nanoparticle-based In Vivo reagent conjugated with siRNA targeting Lamin A/C mRNA or non-silencing control siRNA following the recommended protocol. Tissues were collected and RNA isolated 48 hours after first injection. Samples were analyzed by qRT-PCR for Lamin A/C gene expression levels. Ribosomal RNA levels were used to normalize the Lamin A/C data. Data are means ± SD (n=6).PEG-Liposome In Vivo Transfection Kit for Rodents (Mouse, Rat)PEGylated liposome based reagentEfficient delivery to the spleen, kidney, pancreas, liver, and multiple tumor types via systemic administrationComplete product support information is available at: PEG-Liposome In Vivo Transfection KitFigure 7. Systemic administration (i.v.) of Liposome-PEG based In Vivo reagent conjugated with siRNA targeting Lamin A/C mRNA or non-silencing control siRNA following the recommended protocol. Tissues were collected and RNA isolated 48 hours after first injection. Samples were analyzed by qRT-PCR for Lamin A/C gene expression levels. Ribosomal RNA levels were used to normalize the Lamin A/C data. Data are means ± SD (n=6).Figure 8. Intratumoral administration (i.t.) of Liposome-PEG based In Vivo reagent conjugated with siRNA targeting Lamin A/C mRNA or non-silencing control siRNA following the recommended protocol. Tissues were collected and RNA isolated 48 hours after first injection. Samples were analyzed by qRT-PCR for Lamin A/C gene expression levels. Ribosomal RNA levels were used to normalize the Lamin A/C data. Data are means ± SD (n=6).Tissue-targeted In Vivo Transfection Reagents for Rodents (Mouse, Rat):LIVER-targeted in vivo reagentKIDNEY-targeted in vivo reagentPANCREAS-targeted in vivo reagentAll Altogen® In Vivo Transfection Kits supplied with ready-to-run transfection protocols that eliminate the need for extensive transfection optimization experiments. Read more about transfection technology at Altogen’s Transfection Resource.Selected in vivo transfection product citations (ALTOGEN® IN VIVO Transfection Kits used in the following publications):Nature. 2008 454(7203):523-7. Innate immunity induced by composition-dependent RIG-I …Saito et al [PDF]Am J Pathology. 2010 177(4):1870-80. Role of ocular complement factor H in a murine model … Lyzogubov et al [PDF]Nature Biotechnology. 2011 29(4):341-5. Delivery of siRNA to the mouse brain by … Alvarez-Erviti et al [PDF]Cancer Research. 2011 71(15):5144-53. Inhibition of miR-193a expression by… Iliopoulos et al [PDF]RNA. 2010 16(11):2108-19. RNase L releases a small RNA from HCV RNA that refolds … Malathi et al [PDF]Diabetologia. 2012 55(7):2069-79. The p47phox- and NADPH oxidase organiser 1 … Youn et al [PDF]British Journal of Cancer. 2012 107(3):516-26. TIGAR induces p53-mediated cell-cycle … Madan et al [PDF]Hypertension. 2014 63(2):353-61. Tissue transglutaminase contributes to … Liu et al [PDF]Circulation Research. 2010 15;107(8). Kruppel-like factor-4 transcriptionally regulates … Cowan et al [PDF]Hypertension. 2012 59(1):158-66. Role of uncoupled endothelial nitric oxide synthase … Gao et al [PDF]Jounal of Biological Chemistry. 2012 287(4):2907. Chaperoning of mutant p53 protein … Gogna et al [PDF]PLoS Pathogens. 2012 8(8) Uridine composition of the poly-U/UC tract of HCV RNA … Schnell et al [PDF]J Proteome Res. 2012(11) Retinal proteome analysis in a mouse model of oxygen-induced … Kim et al [PDF]J Transl Med. 2010 15;8:133. Prevention of hyperglycemia-induced myocardial apoptosis … Zhang et al [PDF]Mol Cell Biol. 2013 33(7). SCO2 induces p53-mediated apoptosis by Thr845 phosphorylation … Madan et al [PDF]Hypertension. 2015 65(2):430-9. Neurokinin 3 receptor and phosphocholine transferase… Parchim et al [PDF]Gastroenterology. 2011 141(2) Differential type I interferon-mediated autophagic trafficking … Desai et al [PDF]PLoS Pathog. 2014 10(10) Exosomes from hepatitis C infected patients transmit HCV … Bukong et al [PDF]Altogen Biosystems:Altogen Biosystems provides preoptimized transfection products for life science research applications. Transfection protocols are optimized for individual cancer cell lines. Altogen Biosystems developed two types of in vivo delivery kits for animal research: Tissue-targeted reagents (delivery to liver, pancreas, and kidney tissues), and broad range in vivo delivery reagents (PEG-Liposome, Nanoparticle-based, Lipid-based, and Polymer-based kits). Advanced formulation of reagents and optimized transfection protocols provide efficient intracellular delivery of proteins, DNA, RNA, and any other negatively charged molecules in vitro and in vivo. Read more about transfection technology at Altogen’s Transfection Resource.Altogen Labs Research Services:Altogen Labs provides GLP-compliant contract research studies for pre-clinical research, IND applications, and drug development. Biology CRO services include: Xenograft models (30+), development of stable cell lines, ELISA assay development, cell-based and tissue targeted RNAi studies, safety pharm/tox assays, and other studies (visit AltogenLabs.com).

Altogen Biosystems全国代理部分产品列表:

货号

产品

规格

价格(美元)

5030

 

 

 

1703

A204 Transfection Reagent (Rhabdomyosarcoma)

0.5ml

170

1704

A204 Transfection Reagent (Rhabdomyosarcoma)

1.5ml

348

窗体顶端

窗体底端

 

2101

A204 Transfection Reagent (Rhabdomyosarcoma)

1.5ml CRISPR

548

窗体顶端

窗体底端

 

7018

A204 Transfection Reagent (Rhabdomyosarcoma)

8.0ml

1044

窗体顶端

窗体底端

 

1167

A375 Cells Transfection Reagent (CRL-1619)

0.5ml

195

1168

A375 Cells Transfection Reagent (CRL-1620)

1.5ml

427

2102

A375 Cells Transfection Reagent (CRL-1621)

1.5ml CRISPR

627

1169

A375 Cells Transfection Reagent (CRL-1622)

8.0ml

1281

5030

Nanoparticle In Vivo Transfection Reagent

0.5 ml - 10 injections 

445

5010

LIPID In Vivo Transfection Reagent

0.5 ml - 10 injections

405

5040

PEG-Liposome In Vivo Transfection Reagent

0.5 ml - 10 injections

465

5020

POLYMER In Vivo Transfection Reagent

0.5 ml - 10 injections

425

5050

Pancreas In Vivo Transfection Kit

0.5 ml - 10 injections 

495

5060

Liver In Vivo Transfection Kit

0.5 ml - 10 injections 

495

5070

Kidney In Vivo Transfection Kit

0.5 ml - 10 injections 

495

1721

BMS2 Transfection Reagent (Bone Marrow Cells)

0.5 ml 

231

6345

C6 Transfection Reagent (Glioma Cells, CCL-107)

0.5 ml 

199

6803

DLD-1 Transfection Reagent (Colon Cancer, CCL-221)

0.5 ml 

201

1775

HUH-7 Transfection Reagent (Liver Cancer Cells)

0.5 ml 

179

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