产品说明
Biliverdin Hydrochloride is produced from the oxidation of heme in a reaction catalyzed by the enzyme heme oxygenase. Heme oxygenase has been implicated in tumor cell resistance to chemotherapy, reduction of free radical formation, reduction of inflammation, and has been associated with vascular repair. In vivo, biliverdin is reduced to bilirubin. Biliverdin Hydrochloride is soluble in basic aqueous solutions (pH > 9 for intitial dissolution) and soluble down to pH 7 once in solution as well as methanol and ethanol if made slightly basic.References1) Seta, F., L. Bellner, et al. (2006). “Heme Oxygenase-2 Is a Critical Determinant for Execution of an Acute Inflammatory and Reparative Response.” The American Journal of Pathology 169(5): 1612.2) Jozkowicz, A., H. Was, et al. (2007). “Heme oxygenase-1 in tumors: is it a false friend?” Antioxid Redox Signal 9(12): 2099-117.3) Abraham, N. G. and A. Kappas (2005). “Heme oxygenase and the cardiovascular-renal system.” Free Radic Biol Med 39(1): 1-25.4) Kim, D. H., A. P. Burgess, et al. (2008). “Heme oxygenase-mediated increases in adiponectin decrease fat content and inflammatory cytokines tumor necrosis factor-alpha and interleukin-6 in Zucker rats and reduce adipogenesis in human mesenchymal stem cells.” J Pharmacol Exp Ther 325(3): 833-40.5) Overhaus, M., B. A. Moore, et al. (2006). “Biliverdin protects against polymicrobial sepsis by modulating inflammatory mediators.” American Journal of Physiology – Gastrointestinal and Liver Physiology 290(4): G695-G703.6) MacLean, P. D., E. C. Drake, et al. (2007). “Bilirubin as an antioxidant in micelles and lipid bilayers: Its contribution to the total antioxidant capacity of human blood plasma.” Free Radical Biology and Medicine 43(4): 600.CategoriesBiochemical ReagentsFilterHEME PathwayCAS Number55482-27-4Molecular FormulaC33H35ClN4O6Molecular Weight (g/mol)619.2Storage-20 °C or below, protect from light
Echelon产品线
★合成磷脂、磷酸肌醇、鞘脂及其衍生物 |
★脂蛋白质相互作用工具 |
★脂质含量检测试剂盒 ★脂质相关生物酶活性检测,抑制剂筛选试剂盒 |
新品排行榜
1
Echelon/High Throughput Autotaxi...
2
Echelon/Tks5 VHH Antibody/250 ug...
3
Echelon/d5-D-myo-Phosphatidylino...
4
Echelon/Tensin 4 VHH Antibody/25...
5
Echelon/Autotaxin Inhibitor Scre...
6
Echelon/PTEN Activity ELISA Kit/...
7
Echelon/Hyaluronidase Activity E...
8
Echelon/Vinculin VHH Antibody/25...
9
Echelon/Vac14 Antibody, polyclon...
10
Echelon/Autotaxin Activity Assay...
文章排行榜
1
Echelon-inc
2
Echelon-inc
3
eBioscience AccutaseTM细胞分离溶液
4
eBioscience-莱兹生物免疫学技术讲座圆满落幕!
5
Echelon Bioscience公司简介,优势订购!
6
使用eBioscience流式抗体的常见问题
7
Echelon Biosciences 宣布与 ProBioscience Technologies 合作在东南亚分销 - Echelon Biosciences,Ebioscience 现货
8
FierceBiotech:2014年最热门的15家生物公司
9
Echelon Biosciences Incorporated中国采购 Echelon脂质含量检测试剂盒
10
Echelon经销商/代理商 Echelon抑制剂筛选试剂盒