首页 > Echelon > echelon-inc/2-C-Methyl-D-erythritol 4-phosphate (MEP)/5mg/I-M051-5mg

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echelon-inc/2-C-Methyl-D-erythritol 4-phosphate (MEP)/5mg/I-M051-5mg

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I-M051-2

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CatalogNo.: I-M051MW: 260.09CAS: 206440-72-4Description: Isoprenoidcompoundsareadiversegroupofnaturalproductswhichareessentialcomponentsinallcells.Isoprenoidsarebiosynthesizedfromthesimpleprecursorsisopentenyldiphosphate(IPP)anddimethylallyldiphosphate(DMAPP).Eukaryotes,fungi,andsomegram-positivebacteriaproduceIPPthroughthemevalonate(MVA)pathwaywhereasgram-negativeandsomegram-positivebacteriautilizethenon-mevalonateor2-C-methyl-D-erythritol-4-phosphate(MEP)pathway.MEPisformedfrom1-deoxy-D-xylulose5-phosphate(DXP)byMEPSynthase(DXPreductoisomerase)andcoupledwithCMPtoform4-diphosphocytidyl-2-C-methyl-D-erythritol(CDP-ME)byCDPMESynthase.ProvidedasthesodiumsaltStorage-20°Corbelow.FeaturedinPublications:1)Poliquin,K.,Y.V.Ershov,etal.(2004)."Inactivationofsll1556inSynechocystisStrainPCC6803ImpairsIsoprenoidBiosynthesisfromPentosePhosphateCycleSubstratesInVitro."JBacteriol186(14):4685-4693.2)Eoh,H.,A.C.Brown,etal.(2007)."CharacterizationoftheMycobacteriumtuberculosis4-Diphosphocytidyl-2-C-Methyl-d-ErythritolSynthase:PotentialforDrugDevelopment."JournalofBacteriology189(24):8922-8927.3)Lherbet,C.,F.Pojer,etal.(2006)."AbsenceofSubstrateChannelingbetweenActiveSitesintheAgrobacteriumtumefaciensIspDFandIspEEnzymesoftheMethylErythritolPhosphatePathway."Biochemistry45(11):3548Keywords:Methylerythritolphosphate,2-C-Methylerythritol4-phosphate,2-C-methyl-D-erythritol4-phosphate,Methylerythritol4-phosphate

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