产品说明
CatalogNo.: Z-PLBPADescription: Purifiedanti-LBPAmonoclonalantibodySubclass:IgG1k(clone6C4)Source:MouseApplications:Immunofluorescence,ELISAThisantibodyrecognizesanimportantbutunusualeukaryoticlipid,lysobisphosphatidicacid,(LBPA)alsotermedbis(monoacylglyceryl)phosphate(BMP).LBPAisfoundprimarilyinlateendosomesandisacellularMarkerofthiscompartment.Further,LBPAisalipidantigenfortheautoimmunedisorder,anti-phospholipidsyndrome(APS).StorageStoreat-20°Cforupto60days.Apreservativesuchassodiumazide(finalconcentration,0.02%)canbeaddedifitwilnotinterferewithspecificapplications,i.e.peroxidaseactivity.Aliquotandstoreat-20or-70°Ciflongerstorageisnecessary.Avoidrepeatedfreeze/thawcycles.FeaturedinPublications1)Kobayashi,T.,M.H.Beuchat,etal.(1999)."Lateendosomalmembranesrichinlysobisphosphatidicacidregulatecholesteroltransport."NatCellBiol1(2):113-8.2)Zornetta,I.,L.Brandi,etal.(2010)."Imagingthecellentryoftheanthraxoedemaandlethaltoxinswithfluorescentproteinchimeras."CellMicrobiol12(10):1435-45.3)Otomo,T.,K.Higaki,etal.(2011)."LysosomalStorageCausesCellularDysfunctioninMucolipidosisIISkinFibroblasts."JBiolChem286(40):35283-90.RelatedProductsAnti-LBPAAntibody(6C4)incellsupernatant(Z-SLBPA)(S,S)Bisoleoyl-lysobisphosphatidicacid(L-B181)Biotin-(R,R)-2,2’-Bisdodecyl-LBPA(biotin-C12-etherLBPA)(L-B1B12)Anti-LysobisphosphatidicAcid(LBPA)HumanIgGELISA(K-4900)
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