Thisrabbitpolyclonalantibodywasraisedagainstfusionproteinandrecognizeshuman,mouseandratATPBindingCassetteSubfamilyDMember2(ABCD2).Highlights:Reactswithhuman,mouseandratABCD2SuitableforWesternBlotandImmunofluorescenceandImmuneElectronMicroscopyapplicationsABCD2isamemberofthesuperfamilyofATP-bindingcassette(ABC)transporters.ABCproteinstransportvariousmoleculesacrossextra-andintra-cellularmembranes.ABCgenesaredividedintosevendistinctsubfamiliesandthisproteinisamemberoftheALDsubfamily,whichisinvolvedinperoxisomalimportoffattyacidsand/orfattyacyl-CoAsintheorganelle.DiseasesassociatedwithABCD2includeAdrenoleukodystrophyandDemyelinatingDisease.FromthelaboratoryofGregA.Graf,PhD,UniversityofKentucky.SpecificationsAnti-ABCD2AntibodyProductType: AntibodyAntigen: ABCD2peptideAccessionID: GeneID:26874MolecularWeight: 78kDaClonality: PolyclonalReactivity: Mouse,RatandHumanImmunogen: FusionPeptideSpeciesImmunized: RabbitEpitope: Aa377-711Buffer: 50%glycerol,50mMtris(pH7.4)and0.01%azideTestedApplications: WB(1:2000),IF(1:200),IEM(1:50)Storage: -80CShipped: DryIceDataImmunofluorescenceMicroscopyandImmunoblotAnalysisofD2ProteininCulturedCells.(A)CellsweretransfectedwithaplasmidcontainingaCDNAencodingmouseD2.CellswereprocessedforindirectimmunofluorescencemicroscopyusingthepolyclonalD2antibody.Inset:lysatesfromcellstransfectedwithcontrolplasmid(V)andD2wereanalyzedbySDS-PAGEandimmunoblotting.(B)TotalmembraneswerepreparedfromADIposecollectedfromwild-typeandD2-deficient(D2-/-)miceandanalyzedbyimmunoblottingwiththeD2antibody.ProviderFromthelaboratoryofGregA.Graf,PhD,UniversityofKentucky.ReferencesLiuJ,SabevaNS,BhatnagarS,LiXA,PujolA,GrafGA.ABCD2isabundantinadiposetissueandopposestheaccumulationofdietaryerucicacid(C22:1)infat.JLipidRes.2010Jan;51(1):162-8.LiuJ,LiangS,LiuX,BrownJA,NewmanKE,SunkaraM,MorrisAJ,BhatnagarS,LiX,PujolA,GrafGA.TheabsenceofABCD2sensitizesmicetodisruptionsinlipidmetabolismbydietaryerucicacid.JLipidRes.2012Jun;53(6):1071-9.LiuX,LiuJ,LesterJD,PijutSS,GrafGA.ABCD2identifiesasubclassofperoxisomesinmouseadiposetissue.BiochemBiophysResCommun.2015Jan2;456(1):129-34.Ifyoupublishresearchwiththisproduct,pleaseletusknowsowecanciteyourpaper.

在Kerafast，我们不断为我们难以访问的生物研究材料组合添加新试剂。下面列出了我们的新产品。

 

抗豚鼠GnRH [TF60]抗体

产品描述：该兔多克隆抗体针对对应于豚鼠促性腺激素释放激素（GnRH）的肽产生并识别豚鼠GnRH。

提供者：来自新罕布什尔大学Stacia A. Sower博士实验室。

 

PC3-ML-萤光素酶前列腺癌细胞系

PC3-ML萤光素酶细胞系是表达来自转移性骨的萤光素酶表达的前列腺癌细胞。

来自德雷塞尔大学Mauricio J. Reginato博士的实验室。

 

pFA6A-GFP-ura4MX6质粒

使用pFA6A-GFP-ura4MX6质粒进行基因组GFP标记以在裂殖酵母粟酒裂殖酵母中表达C末端GFP融合蛋白。

Bicyclo[4.2.0]oct-(8)-ene-8-carbonitrile AROMP Polymer

方便制备双环[4.2.0]辛 - （8） - 烯-8-甲腈，其可用于制备醛单体以及其他用于聚合的单体。