SpecificationRelated ProductsCat.No. :Kit-2318Product Overview :5-Lipoxygenase (5-LOX) is a non-heme iron-containing dioxygenase that converts unsaturated fatty acids to epoxides; for example the synthesis of leukotrienes from arachidonic acid. It is involved in processes like cell proliferation, differentiation and inflammation and has been implicated in inflammation and hyper proliferation mediated diseases like asthma, rheumatoid arthritis and cancer. Research for identifying potential remedies for such diseases involves the identification of inhibitors of 5-lipoxygenase. 5-Lipoxygenase Inhibitor Screening Kit uses Zileuton, a well-known 5-lipoxygenase inhibitor as positive control, and provides a simple and fast method to screen/ characterize potential 5-lipoxygenase inhibitors.Storage :Upon arrival, store the kit at -80°C, protected from light. Briefly centrifuge small vials before opening. Read entire protocol before performing the assay. Components are stable for at least three months. LOX Assay Buffer: Warm to room temperature before use. LOX Probe and Zileuton: Aliquot and store at -80ºC in the dark. LOX Substrate: Store at -80ºC.5-LOX Enzyme: Aliquot and store at -80ºC. Avoid repeated freeze thaw cycles. Note: Keep all components on ice while performing the assay.Size :100 assaysProducts Types◆ Recombinant Protein LOX-4734HRecombinant Human LOX Protein, GST-tagged+Inquiry LOX-628RRecombinant Rat LOX Protein (163-411 aa), His-tagged+Inquiry LOX-9184MRecombinant Mouse LOX Protein+Inquiry LOX-7911HRecombinant Human LOX protein, His & GST-tagged+Inquiry LOX-189HRecombinant Human LOX protein, GST-tagged+Inquiry See All LOX Recombinant Protein ◆ Native Protein LOX-41Native Lactate Oxidase+Inquiry See All LOX Native Protein ◆ Lysates LOX-4677HCLRecombinant Human LOX 293 Cell Lysate+Inquiry See All LOX Lysates ◆ Assay kits Kit-1061Lipoxygenase Activity Assay Kit (Fluorometric)+Inquiry Kit-0520LOX Fluorometric Assay Kit+Inquiry See All LOX Assay kits Related GeneLOX