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enogene/LY-294002PI3K Inhibitor/E1B1737
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产品说明
LY-294002PI3K InhibitorPDFCatalog Number:E1B1737Amount:PHYSICAL APPEARANCE: Off-white-pale yellow solid (m.p. 182-184°C)MOLECULAR FORMULA: C19H17NO3Molecular Weight: 307.4Purity: 99% (TLC)Solubility: Soluble in DMSO (25 mg/ml warm) and ethanol (25 mg/ml warm)Storage/Stability: Store, as supplied, at -20°C for up to 1 year. Store solutions at -20°C for up to 3 months.Recommended Dilutions: Potent, cell permeable and specific inhibitor of phosphatidylinositol 3- kinase (IC50 = 1.4 μM; purified PI 3-kinase). Does not significantly inhibit PKC, PKA, MAP kinase, S6 kinase, EGFrK, c-src kinase, PI 4-kinase, DAG kinase or rabbit kidney ATPase at concentrations of 50 μM. In intact neutrophils stimulated with fMet-Leu-Phe, LY 294002 completely abolished PI 3-kinase activity at 50 μM without cell toxicity. Also blocked proliferation of cultured rabbit aortic smooth muscle cells without cell death. Induces apoptosis.References:1​ C.J.Vlahos et al. J.Biol.Chem. 1994 269 52412​ V.Sanchez Margalet et al. Biochem.Biophys.Res.Commun. 1994 204 4463​ T.J.Kovacsovics et al. J.Biol.Chem. 1995 270 113584​ R.Yao and G.M.Cooper Science 1995 267 2003The pharmacological and toxicological properties of this product have not been fully investigated. Exercise caution in use and handling. This product must not be used in humans.Price:55$

enogene的β-actin小鼠单克隆抗体(A02)PDF

目录编号:E12-045

量:100微克/ 100微升

克隆编号:A02

背景:β-肌动蛋白是已鉴定出的六种不同的肌动蛋白同工型之一。在各种物种和组织的细胞中发现的肌动蛋白分子在免疫学和物理特性方面趋于非常相似。因此,针对β-肌动蛋白的抗体可用作蛋白质印迹的上样对照。但是,应注意,β-肌动蛋白的水平在某些细胞中可能不稳定。例如,β-肌动蛋白在脂肪组织中的表达非常低,因此不应将β-肌动蛋白用作这些组织的负荷控制。

抗体形式:pH 7.4、150mM NaCl,0.02%叠氮化钠和50%甘油的磷酸盐缓冲盐水(不含Mg2 +和Ca2 +)中的小鼠IgG1。

储存/稳定性:-20℃/ 1年保存

特异性/敏感性:抗体可以检测内源性β-肌动蛋白。

反应性:H,R,M,Mk,Dg,Ch,Hm,Rb,Pg,Sh

应用范围:WB:1:5,000-10,000 IHC:1:200 IF:1:200