Tocris产品促销 Tocris GPCR ligands,Tocris/BRACO 19 trihydrochloride/5312/10/10 mg,DNA聚合酶,核酸酶类,分子类,,Tocris Bioscience蚂蚁淘商城

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Tocris/BRACO 19 trihydrochloride/5312/10/10 mg

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Tocris/BRACO 19 trihydrochloride/5312/10/10 mg

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Tocris Bioscience

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5312/10

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4000-520-616

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Description:Telomeraseinhibitor

ChemicalName:N,N'-[9[[4-(Dimethylamino)phenyl]amino]-3,6-acridinediyl]bis-1-pyrrolidinepropanamidetrihydrochloride

Purity:≥95%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Telomeraseinhibitor(IC₅₀=115nM).Inhibitsexpressionofhumantelomerasereversetranscriptase(hTERT),inducescellularsenescenceandinhibitsgrowthofuterinecancercellsinvitro.Inhibitsgrowthofuterinetumorxenograftsinmice.

TechnicalData

M.Wt	703.14
Formula	C₃₅H₄₃N₇O₂.3HCl
Storage	Storeat-20°C
Purity	≥95%(HPLC)
CASNumber	1177798-88-7
PubChemID	10349800
InChIKey	MJAPNWJRLLDPAB-UHFFFAOYSA-N
Smiles	O=C(CCN5CCCC5)NC3=CC2=NC1=CC(NC(CCN6CCCC6)=O)=CC=C1C(NC4=CC=C(N(C)C)C=C4)=C2C=C3.Cl.Cl.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	35.16	50
	water	35.16	50

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight703.14.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	1.42mL	7.11mL	14.22mL
5mM	0.28mL	1.42mL	2.84mL
10mM	0.14mL	0.71mL	1.42mL
50mM	0.03mL	0.14mL	0.28mL

ProductDatasheets

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