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Tocris/NAB 2/5131/10/10 mg
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Tocris/NAB 2/5131/10/10 mg
品牌 / 
Tocris Bioscience
货号 / 
5131/10
美元价:
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数    量:
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4000-520-616
Description:Protectsagainstα-synucleintoxicity;promotesRsp5/Nedd4-dependentendosomaltransport
ChemicalName:N-[(2-Chlorophenyl)methyl]-1-(2,5-dimethylphenyl)-1H-benzimidazole-5-carboxamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Protectsagainstα-synucleintoxicity.Reversestheα-synuclein-inducedpathologicalphenotypeinParkinson'sdiseasecorticalneurons.PromotesE3ubiquitinligaseRsp5/Nedd4-dependentendosomaltransport.

LicensingInformation

SoldunderlicensefromWhiteheadInstituteforBiomedicalResearch.

CompoundLibraries

NAB2isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt389.88
FormulaC23H20ClN3O
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber1504588-00-4
PubChemID82017756
InChIKeyCZSLEMCYYGEGKP-UHFFFAOYSA-N
SmilesO=C(NCC4=C(Cl)C=CC=C4)C1=CC=C2C(N=CN2C3=CC(C)=CC=C3C)=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO38.99100
ethanol38.99100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight389.88.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.56mL12.82mL25.65mL
5mM0.51mL2.56mL5.13mL
10mM0.26mL1.28mL2.56mL
50mM0.05mL0.26mL0.51mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet