商品信息
联系客服
郑重提醒:
无质量问题不接受退换货,下单前请仔细核对信息。
下单后请及时联系客服核对商品价格,订单生效后再付款。
Tocris/NAB 2/5131/10/10 mg
免费咨询热线
4000-520-616
Description:Protectsagainstα-synucleintoxicity;promotesRsp5/Nedd4-dependentendosomaltransport
ChemicalName:N-[(2-Chlorophenyl)methyl]-1-(2,5-dimethylphenyl)-1H-benzimidazole-5-carboxamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Protectsagainstα-synucleintoxicity.Reversestheα-synuclein-inducedpathologicalphenotypeinParkinson'sdiseasecorticalneurons.PromotesE3ubiquitinligaseRsp5/Nedd4-dependentendosomaltransport.
LicensingInformation
SoldunderlicensefromWhiteheadInstituteforBiomedicalResearch.
CompoundLibraries
NAB2isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
M.Wt | 389.88 |
Formula | C23H20ClN3O |
Storage | Storeat+4°C |
Purity | ≥98%(HPLC) |
CASNumber | 1504588-00-4 |
PubChemID | 82017756 |
InChIKey | CZSLEMCYYGEGKP-UHFFFAOYSA-N |
Smiles | O=C(NCC4=C(Cl)C=CC=C4)C1=CC=C2C(N=CN2C3=CC(C)=CC=C3C)=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 38.99 | 100 | |
ethanol | 38.99 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight389.88.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.56mL | 12.82mL | 25.65mL |
5mM | 0.51mL | 2.56mL | 5.13mL |
10mM | 0.26mL | 1.28mL | 2.56mL |
50mM | 0.05mL | 0.26mL | 0.51mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet
▍
品牌分类
▍
官网分类
▍
品牌问答
暂无品牌问答