外泌体参与细胞间通讯，目前对外泌体的研究兴趣日益增长，小编整理一些外泌体相关的数据库，供研究者学习使用。

ExosomeDatabase

www.ExosomeData.com

EVpedia--Databaseofexosomalproteome,transcriptome,andlipidome

http://www.evpedia.info/

Apublicdatabaseforextracellularvesiclesresearch.

EVpediaisanintegratedandcomprehensiveproteome,transcriptome,andlipidomedatabaseofEVsderivedfromarchaea,bacteria,andeukarya,includinghuman.

EVpediaprovidesanarrayoftools,suchassearchandbrowsetoolsforvesicularproteins,comparisonofvesiculardatasetsbyorthologidentification,GeneOntologyenrichmentanalysesandnetworkanalysesofvesicularproteins.FurThermore,EVpediaprovidesdatabasesofvesicularmRNAs,miRNAs,andlipids.Thus,EVpediamightserveasausefulcommunityresourcetotriggertheadvancementofsystematicandcomprehensivestudiesofEVsandtounveilthefundamentalrolesofEVs.

ExoCarta--Databaseofexosomalproteins,RNAandlipids.

www.exocarta.org/

ExoCarta:databaseofexosomalproteins,RNAandlipids.

ExoCarta,anexosomedatabase,provideswiththecontentsthatwereidentifiedinexosomesinmultipleorganisms.

Vesiclepedia--Databaseofexosomalproteins,RNAandlipids

http://www.microvesicles.org/

Acommunitycompendiumforextracellularvesicles

Vesiclepedia,amanuallycuratedcompendiumofmoleculardata(lipid,RNAandprotein)identifiedindifferentclassesofEVs.Currently,Vesiclepediacomprises35,264protein,18,718mRNA,1,772miRNAand342lipidentriesencompassedfrom341independentstudiesthatwerepublishedoverthepastseveralyears.

ExosomeGeneOntologyAnnotationInitiative

http://www.ebi.ac.uk/GOA/exosome

Thisinitiative,undertakenbytheUniProtcuratorsattheEBI,involvesthemanualassignmentofGOannotationstohumanexosomalproteinsbycuratorsreADIngthescientificliteratureandassigningtotheproteinsGOtermsthatdescribetheirBIOLOGicalroles.CuratorsworkingonthisprojectarerequestingnewGOtermsspecifictoexosomeproteinbiologytofullycaptureliteraturefindings.

exoRBase--DatabaseofexosomalcircRNA、LncRNAandmRNA

http://www.exorbase.org/

exoRBaseisarepositoryofcircularRNA(circRNA),longnon-codingRNA(lncRNA)andmessengerRNA(mRNA)derivedfromRNA-seqdataanalysesofhumanbloodexosomes.Experimentalvalidationsfrompublishedliteraturearealsoincluded.

exoRBasefeaturestheintegrationandvisualizationofRNAexpressionprofilesbasedonnormalizedRNA-seqdataspanningbothnormalindividualsandpatientswithdifferentdiseases.

UrinaryExosomeProteinDatabase

https://hpcwebapps.cit.nih.gov/ESBL/Database/Exosome/

ThisdatabaseofurinaryexosomeproteinsisbasedonpublishedproteinmassspectrometrydatafromtheNHLBIEpithelialSystemsBiologyLaboratory(ESBL).Alldataarefromurinaryexosomesisolatedfromhealthyhumanvolunteers.

Thiscurrentdatabasecontainsproteinidentificationofhumanurinaryexosomesusingtwodifferentmassspectrometeranalyzers.

exRNAAtlas--DatabaseofexosomalRNA

http://exrna-atlas.org/

TheexRNAAtlasisthedatarepositoryoftheExtracellularRNACommunicationConsortium(ERCC),whichincludessmallRNAsequencingandRT-qPCR-derivedexRNAprofilesfromhumanandmousebiofluids.AllRNA-seqdatasetsareprocessedusingversion4oftheexceRptsmallRNA-seqpipelineandERCC-developedqualitymetricsareuniformlyappliedtothesedatasets.

editedbyAlexfromUmibio(Shanghai)Co.Ltd

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