商品信息
联系客服
郑重提醒：
无质量问题不接受退换货，下单前请仔细核对信息。
下单后请及时联系客服核对商品价格，订单生效后再付款。
Tocris/B I09/6009/10/10 mg
免费咨询热线
4000-520-616
Description:IRE1endonucleaseinhibitor;cellpermeable
ChemicalName:7-(1,3-Dioxan-2-yl)-1,2,3,4-tetrahydro-8-hydroxy-5H-[1]benzopyrano[3,4-c]pyridin-5-one
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
IRE-1RNaseinhibitor(IC50=1.23μM).InhibitsIRE-1/XBP1pathway.Cellpermeable.Inhibitsgrowthofhumanchroniclymphocyticleukemia(CLL)cellsinvitroandpromotesCLLregressioninamousemodel.
TechnicalData
| M.Wt | 303.31 |
| Formula | C16H17NO5 |
| Storage | Storeat-20°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 1607803-67-7 |
| PubChemID | 86290458 |
| InChIKey | UYYMWNUDIOPESF-UHFFFAOYSA-N |
| Smiles | OC1=CC=C2C3=C(C(OC2=C1C4OCCCO4)=O)CNCC3 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 15.17 | 50 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight303.31.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.3mL | 16.48mL | 32.97mL |
| 5mM | 0.66mL | 3.3mL | 6.59mL |
| 10mM | 0.33mL | 1.65mL | 3.3mL |
| 50mM | 0.07mL | 0.33mL | 0.66mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
Thereconstitutioncalculatorallowsyoutoquicklycalculatethevolumeofareagenttoreconstituteyourvial.Simplyenterthemassofreagentandthetargetconcentrationandthecalculatorwilldeterminetherest.
我要提问
您的问题将推送给已购用户，TA们将会为你解答。