BiologicalActivity
LoopdiureticthatinhibitstheNa+/2Cl-/K+(NKCC)cotransporter.Morepotentthanfurosemide(Cat.No.3109).
CompoundLibraries
BumetanideisalsoofferedaspartoftheTocriscreenPlusandTocriscreenLibraryofFDA-ApprovedCompounds.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
| M.Wt | 364.42 |
| Formula | C17H20N2O5S |
| Storage | StoreatRT |
| Purity | ≥99%(HPLC) |
| CASNumber | 28395-03-1 |
| PubChemID | 2471 |
| InChIKey | MAEIEVLCKWDQJH-UHFFFAOYSA-N |
| Smiles | CCCCNC1=CC(C(O)=O)=CC(S(=O)(N)=O)=C1OC2=CC=CC=C2 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 36.44 | 100 | |
| ethanol | 27.33 | 75 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight364.42.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.74mL | 13.72mL | 27.44mL |
| 5mM | 0.55mL | 2.74mL | 5.49mL |
| 10mM | 0.27mL | 1.37mL | 2.74mL |
| 50mM | 0.05mL | 0.27mL | 0.55mL |
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