Tocris产品目录价格 Tocris Bioscience型号参数规格,Tocris/SEA 0400/6164/50/50 mg,转运体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/SEA 0400/6164/50/50 mg

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Tocris Bioscience

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6164/50

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4000-520-616

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Description:PotentNa⁺/Ca²⁺exchanger(NCX)inhibitor.

ChemicalName:2-[4-[(2,5-Difluorophenyl)methoxy]phenoxy]-5-ethoxybenzenamine

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentNa⁺/Ca²⁺exchanger(NCX)inhibitor.InhibitsNCXactivityinratastrocytes,microgliaandculturedneurons,caninecardiacsarcolemmalvesiclesandratcardiomyocytes(IC₅₀valuesare5and8.3,33,90and92nM,respectively).Reducesinfarctvolumesandexhibitsprotectiveeffectsagainstmyocardialischemiainrats.

TechnicalData

M.Wt	371.38
Formula	C₂₁H₁₉F₂NO₃
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	223104-29-8
PubChemID	644100
InChIKey	YSUBLPUJDOWYDP-UHFFFAOYSA-N
Smiles	CCOC1=CC(N)=C(C=C1)OC2=CC=C(C=C2)OCC3=C(C=CC(F)=C3)F

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	37.14	100
	ethanol	37.14	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight371.38.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.69mL	13.46mL	26.93mL
5mM	0.54mL	2.69mL	5.39mL
10mM	0.27mL	1.35mL	2.69mL
50mM	0.05mL	0.27mL	0.54mL

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