Tocris产品目录价格 Tocris配体,Tocris/GW 501516/5674/50/50 mg,摇床,Tocris,Bio-Techne,,50 mg蚂蚁淘商城

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Tocris/GW 501516/5674/50/50 mg

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Tocris Bioscience

货号 /

5674/50

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4000-520-616

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Description:PotentandselectivePPARδagoNIST

ChemicalName:2-[2-Methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methyl]thio]phenoxy]aceticacid

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectivePPARδagonist(EC₅₀=1.2nM).Displays<1000-fold selectivity="" over="" other="" ppar="" subtypes.="" increases="" abc="" a1="" transporter="" expression="" and="" induces="" apolipoprotein="" a1-mediated="" cholesterol="" efflux="">invitro.AlsoincreaseserumHDLcholesterolandlowerssmall,denseLDLlevelsinobesityinvivomodels.

TechnicalData

M.Wt	453.5
Formula	C₂₁H₁₈F₃NO₃S₂
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	317318-70-0
PubChemID	9803963
InChIKey	YDBLKRPLXZNVNB-UHFFFAOYSA-N
Smiles	CC1=CC(SCC2=C(C)N=C(C3=CC=C(C(F)(F)F)C=C3)S2)=CC=C1OCC(O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	45.35	100
	ethanol	22.68	50

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight453.5.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.21mL	11.03mL	22.05mL
5mM	0.44mL	2.21mL	4.41mL
10mM	0.22mL	1.1mL	2.21mL
50mM	0.04mL	0.22mL	0.44mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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