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Adipogen/Takeda-6d/SYN-1168-M050/50 mg

  
  2024-04-28
  
More Information Product Details Synonyms Product Type Properties Formula MW CAS Purity Chemicals Appearance Solubility Declaration Other Product Data InChi Key Shipping and Handling Shipping Short Term Storage Long Term Storage Use/Stability Documents MSDS Product Specification Sheet Datasheet
Takeda 6d
Chemical
C27H19ClFN5O3S
548.0
1125632-93-0
≥95%
Solid.
Soluble in DMSO.
Manufactured by SynKinase.
Target: B-RAF - VEGFR2 | Kinase Group: TKL | Substrate: Serine-ThreonineClick here for Original Manufacturer Product DatasheetOur product description may differ slightly from the original manufacturers product datasheet.
MDPMAXSABUPRJI-UHFFFAOYSA-N
AMBIENT
+4°C
-20°C
Stable for at least 2 years after receipt when stored at -20°C.
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Takeda-6d has potent inhibitory activity in both B-RAF with an IC(50) of 7.0nM and VEGFR2 with an IC(50) of 2.2nM.Product References
  • Design and synthesis of novel DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitors. 1. Exploration of [5,6]-fused bicyclic scaffolds: M. Okaniwa, et al.; J. Med. Chem. 55, 3452 (2012)
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