Biosensis/Mouse antibody to human CDNF (conserved dopamine neurotrophic factor) [7D6]: IgG/M-1677-10
| Description | CDNF (conserved dopamine neurotrophic factor) is a trophic factor for midbrain dopamine neurons in vivo. It prevents the 6-OHDA- (Lindholm et al. 20007; Voutilainen et al., 2011) and MPTP-induced degeneration (Airavaara et al., 2012) of dopamine neurons in rodent models of Parkinsons disease. When administered after 6-OHDA or MPTP lesioning it restores the dopaminergic function and prevents degeneration of dopamine neurons in substantia nigra pars compacta. |
| Batch No. | See product label |
| Unit size | 100 ug |
| Antigen | Recombinant human CDNF protein produced using CHO-based cell line. Purified from cell culture supernatant. |
| Antibody Type | Monoclonal |
| Isotype | IgG1 |
| Other Names | ARMETL1 |
| Produced in | Mouse |
| Purity | Purified by protein G affinity chromatography |
| Applications | Western blot (WB) at a suggested dilution of 1:2,000 1:4,000. Biosensis recommends optimal dilutions/concentrations should be determined by the end user. |
| Specificity | CDNF (conserved dopamine neurotrophic factor) |
| Species Against | Human |
| Form | PBS pH 7.4, with 0.1% sodium azide. |
| Storage | Store at 20°C or -70°C upon receipt. After opening maintain undiluted in smaller aliquots at 20°C or -70°C for up to 6 months. Avoid multiple freeze-thaw cycles. |
| Expiry Date | Unopened, 12 months after purchase. |
