More Information Product Details
Synonyms | XL184; BMS-907351 |
Product Type | Chemical |
Properties
Formula | C28H24FN3O5 |
MW | 501.5 |
CAS | 849217-68-1 |
Purity Chemicals | ≥95% |
Appearance | Solid. |
Solubility | Soluble in DMSO or ethanol. |
Declaration | Manufactured by SynKinase. |
Other Product Data | Target: PDGFR | Kinase Group: RTK | Substrate: TyrosineClick here for Original Manufacturer Product DatasheetOur product description may differ slightly from the original manufacturers product datasheet. |
InChi Key | ONIQOQHATWINJY-UHFFFAOYSA-N |
Shipping and Handling
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
Documents
MSDS ![](\"https://www.ebiomall.com/images/adipogen/download.png\") Download PDF |
Product Specification Sheet
Datasheet | Download PDF |
Cabozantinib is very potent inhibitor, with an IC(50) of less than 10nM for VEGFR2, MET, Kit and FLT3-ITD.Product References
Activity of XL184 (Cabozantinib), an oral tyrosine kinase inhibitor, in patients with medullary thyroid cancer: R. Kurzrock, et al.; J. Clin. Oncol. 29, 2660 (2011)
