- Description
- Product Info
- Shipping and Storage
- Downloads
- References
Description
Daidzin is a soy isoflavone and the parent compound of aglycone daidzein; it is also a phytoestrogen. Daidzin exhibits estrogenic, neuromodulatory, cognition enhancing, and antioxidative activities. Daidzin reverses scopolamine-induced memory impairments in animal models undergoing Morris water maze and passive avoidance tests. Additionally, daidzin inhibits DGalN/LPS-induced increases in aminotransferase activity, lipid peroxidation, and TNF-α levels, preventing hepatocyte apoptosis in other animal models. This compound promotes proliferation of osteoblasts and bone marrow stromal cells and osteogenesis in marrow stromal cells; it also inhibits adipocytic differentiation in osteoblasts.
Product Info
552-66-9 |
≥98% |
C21H20O9 |
416.38 |
3-(4-hydroxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one |
234-236°C |
White powder |
Shipping and Storage
Ambient |
Ambient |
Downloads
D0033 MSDS PDF |
D0033 Info Sheet PDF |
References
Kim DH, Jung HA, Park SJ, et al. The effects of daidzin and its aglycon, daidzein, on the scopolamine-induced memory impairment in male mice. Arch Pharm Res. 2010 Oct;33(10):1685-90. PMID: 21052945.
Kim SH, Heo JH, Kim YS, et al. Protective effect of daidzin against D-galactosamine and lipopolysaccharide-induced hepatic failure in mice. Phytother Res. 2009 May;23(5):701-6. PMID: 19107740.
Li XH, Zhang JC, Sui SF, et al. Effect of daidzin, genistin, and glycitin on osteogenic and adipogenic differentiation of bone marrow stromal cells and adipocytic transdifferentiation of osteoblasts. Acta Pharmacol Sin. 2005 Sep;26(9):1081-6. PMID: 16115375.
