More Information Product Details
Synonyms | LY-2784544 |
Product Type | Chemical |
Properties
Formula | C23H25ClFN7O |
MW | 469.9 |
CAS | 1229236-86-5 |
Purity Chemicals | ≥95% |
Appearance | Solid. |
Solubility | Soluble in DMSO or ethanol. |
Declaration | Manufactured by SynKinase. |
Other Product Data | Target: JAK2 | Kinase Group: PTK | Substrate: TyrosineClick here for Original Manufacturer Product DatasheetOur product description may differ slightly from the original manufacturers product datasheet. |
InChi Key | SQSZANZGUXWJEA-UHFFFAOYSA-N |
Shipping and Handling
Shipping | AMBIENT |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Use/Stability | Stable for at least 2 years after receipt when stored at -20°C. |
Documents
MSDS ![](\"https://www.ebiomall.com/images/adipogen/download.png\") Download PDF |
Product Specification Sheet
Datasheet | Download PDF |
LY2784544 is a potent JAK2 inhibitor with IC(50) of 3nM, effective in JAK2V617F, 8- and 20-fold selective versus JAK1 and JAK3. Phase 2.Product References
Discovery and characterization of LY2784544, a small-molecule tyrosine kinase inhibitor of JAK2V617F: L. Ma, et al.; Blood Cancer J. 3, e109 (2013)
