ETA 受体肽 |多肽 | Tocris 生物科学,Tocris/XCC/4220/10/10 mg-蚂蚁淘生物

Description: Adenosine receptor antagonist Chemical Name: 2-[4-(2,3,6,7-Tetrahydro-2,6-dioxo-1,3-dipropyl-1H-purin-8-yl)phenoxy]-acetic acid Purity: ≥98% (HPLC) Biological Activity Technical Data Solubility Calculators DatasheetsReferences

Biological Activity

Adenosine receptor antagonist (K_i values are 42, 68 and 1130 nM for A₁, A_2B and A_2A receptors).

Technical Data

M. Wt	386.4
Formula	C₁₉H₂₂N₄O₅
Storage	Desiccate at RT
Purity	≥98% (HPLC)
CAS Number	96865-83-7
PubChem ID	126079
InChI Key	QTMMGCYGCFXBFI-UHFFFAOYSA-N
Smiles	O=C1N(CCC)C(C(NC(C3=CC=C(OCC(O)=O)C=C3)=N2)=C2N1CCC)=O

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM Solubility

DMSO

19.32

Preparing Stock Solutions

The following data is based on the product molecular weight 386.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg

1 mM	2.59 mL	12.94 mL	25.88 mL
5 mM	0.52 mL	2.59 mL	5.18 mL
10 mM	0.26 mL	1.29 mL	2.59 mL
50 mM	0.05 mL	0.26 mL	0.52 mL

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Product Datasheets

Certificate of Analysis / Product Datasheet Safety Datasheet Select another language: English German French Spanish View SDS

References

References are publications that support the products\' biological activity.

Jarvis et al (1989) Autoradiographic characterization of high-affinity adenosine A₂ receptors in the rat brain. Brain Res. 484 111 PMID: 2713675

Sebastiao et al (1990) The inhibitory adenosine receptor at the neuromuscular junction and hippocampus of the rat: antagonism by 1,3,8-substituted xanthines. Br.J.Pharmacol. 101 453 PMID: 2257444

Thummler and Dunwiddie (2000) Adenosine receptor antagonists induce persistent bursting in the rat hippocampal CA3 region via an NMDA receptor-dependent mechanism. J.Neurophysiol. 83 1787 PMID: 10758091

Keywords: XCC, supplier, XCC, adenosine, antagonists, Non-selective, Adenosine, Non-selective, Adenosine, Tocris Bioscience