Alpha Synuclein Antibody Properties Description Anti-alpha Synuclein (Mouse) Antibody - 500-301-E56 Host Mouse Target Species Human Known Cross Reactivity human, mouse, rat Clonality Monoclonal 3H9 IgG Application ELISA : 1:10,000 IF Microscopy : 1:500 Western Blot : 1:1000 Physical State Liquid Shipping Condition Dry Ice Format ASCITES Label Unconjugated Preservative 0.01% (w/v) Sodium Azide GeneName SNCA Relevant Links UniProtKB - P37840GeneID - 6622UniProtKB - P37840.1

Alpha Synuclein Antibody Description

Background Alpha Synuclein Antibody detects Alpha Synuclein protein. Alpha-synuclein is a presynaptic neuronal protein that is thought to be involved in the formation of SNARE complexes. Most significantly, aggregated alpha-synuclein is one of the major components found in the Lewy bodies that occur in Parkinson’s disease (PD) and other neurodegenerative disorders. Early onset Parkinsons disease may be caused by a duplication or triplication of one of the alpha synuclein genes. Alpha-synuclein is also found in the Lewy bodies of patients with diffuse Lewy body disease and inclusions in glial cells in the brains of patients with multiple system atrophy (MSA) and amyotrophic lateral sclerosis (ALS). Anti-Alpha-synuclein antibody is ideal for investigators involved in Cell Signaling, Neuroscience, Signal Transduction research. Synonyms mouse anti-Alpha Synuclein Antibody, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, NACP Immunogen Anti-Alpha Synuclein Antibody was produced by repeated immunizations with full length human alpha synuclein. Immunogen Type Recombinant Protein Storage Condition Store vial at -20° C prior to opening.  This product is stable at 4° C as an undiluted liquid.  For extended storage, aliquot contents and freeze at -20° C or below.  Avoid cycles of freezing and thawing. Dilute only prior to immediate use. Application Note Alpha Synuclein antibody is suitable for use in ELISA, Western Blotting and IF. Specific conditions should be optimized by the end user. Expect a band of approximately 15 kDa in size corresponding to the alpha synuclein proteins in the appropriate cell lysate or extract. Purity/Specifity Anti-Alpha Synuclein Antibody is directed against humand Alpha Synuclein protein. The antibody was produced from clarified mouse ascetic fluid. Reactivity is expected against alpha synuclein from most mammalian species based on 100% sequence homology. Cross reactivity with Alpha Synuclein from other sources has not been determined. Disclaimer Note-General This product is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information. All products of animal origin manufactured by Rockland Immunochemicals are derived from starting materials of North American origin. Collection was performed in United States Department of Agriculture (USDA) inspected facilities and all materials have been inspected and certified to be free of disease and suitable for exportation. All properties listed are typical characteristics and are not specifications. All suggestions and data are offered in good faith but without guarantee as conditions and methods of use of our products are beyond our control. All claims must be made within 30 days following the date of delivery. The prospective user must determine the suitability of our materials before adopting them on a commercial scale. Suggested uses of our products are not recommendations to use our products in violation of any patent or as a license under any patent of Rockland Immunochemicals, Inc. If you require a commercial license to use this material and do not have one, then return this material, unopened to: Rockland Inc., P.O. BOX 5199, Limerick, Pennsylvania, USA.