ORDERING INFORMATION

Catalog No.

16801

Clone No.

VP10-115.2

MAb Subtype

IgG1

Size

100ug, 500ug

Library Pack No.

168101

100ug/clone

All 5 clones

16802

VP10-201.7

IgG1

100ug, 500ug

16803

VP10-234.5

IgG1

100ug, 500ug

16804

VP13-607.1

IgG1

100ug, 500ug

16805

VP13-615.3

IgG1

100ug, 500ug

Format: Protein G-purified antibody in PBS, pH 7.4.

BACKGROUND

Valproic acid is primarily used to treat epilepsy and bipolar disorder and to prevent migraine headaches. It has recently been shown to protect against a seizure- induced reduction in phosphatidylinositol (3,4,5)-trisphosphate (PIP3) as a potential therapeutic mechanism. In addition, its anticonvulsant effect has been attributed to the blockade of voltage- dependent sodium channels and increased brain levels of gamma-aminobutyric acid (GABA).

Valproic acid was first made in 1881 and came into medical use in 1962. It is on the World Health Organization\'s List of Essential Medicines.

SPECIFICATION SUMMARY

Antigen: Valproic acid conjugated to KLH.

Host Species: Mouse

Specificity: These antibodies recognize valproic acid.

APPLICATIONS

These antibodies have been qualified for use in ELISA to detect valproic acid.

DILUTION INSTRUCTIONS

Dilute in PBS or medium that is identical to that used in the assay system.

STORAGE AND STABILITY

These antibodies are stable for at least one (1) year at -20oC to -70oC. Store product in appropriate aliquots to avoid multiple freeze-thaw cycles.

For in vitro investigational use only. Not for use in therapeutic or diagnostic procedures.