597-FTO|FTO Antibody抗体(Mouse monoclonal) phosphosolutions代理

Mouse monoclonal antibody

Antigen/Purification:Expand

Biological Significance:Expand

Anti-FTO (Fat mass and obesityassociatedprotein) AntibodyCatalog #: 597-FTO Size: 100 µlIsotype: IgG Clone: 5-2H10Western blot of rat testes lysate showing specificimmunolabeling of the ~58 kDa FTO protein.Page 2 of 2Application Key: WB = Western Blot IF = Immunofluorescence IHC = Immunohistochemistry IP = ImmunoprecipitationSpecies Reactivity Key: All-All Species A-Avian Amp-Amphibian Ar-Arabidopsis B-Bovine C-Canine Ch-Chicken D-DrosophilaGP-Guinea Pig H-Human Ha-Hamster M-Mouse NHP- Non-human primate P-Pig R-Rat S-Sheep X-Xenopus Z-Zebrafish*Species assumed based on 100% homology with sequence used as antigen For Research Use OnlyProduct Specific References:Zhou, J., Wan, J., Gao, X., Zhang, X., Jaffrey, S. R., & Qian, S. B. (2015). Dynamic m6A mRNA methylation directstranslational control of heat shock response. Nature, 526(7574), 591-594.Gulati, P., Avezov, E., Ma, M., Antrobus, R., Lehner, P., O\'Rahilly, S., & Yeo, G. S. (2014). Fat mass and obesityrelated(FTO) shuttles between the nucleus and cytoplasm. Bioscience reports, 34(5), 621-628.Gulati P, Cheung MK, Antrobus R, Church CD, Harding HP, Tung YC, Rimmington D, Ma M, Ron D, Lehner PJ,Ashcroft FM, Cox RD, Coll AP, O\'Rahilly S, Yeo GS (2013) Role for the obesity-related FTO gene in the cellularsensing of amino acids. Proc Natl Acad Sci U S A. Jan 28.General References:Fischer J, Koch L, Emmerling C, Vierkotten J, Peters T, Brüning JC, Rüther U. (2009). Inactivation of the Fto geneprotects from obesity. Nature 458: 894.Fredriksson R, Hägglund M, Olszewski PK, Stephansson O, Jacobsson JA, Olszewska AM, Levine AS, Lindblom J,Schiöth HB (2008). The obesity gene, FTO, is of ancient origin, upregulated during food deprivation and expressed inneurons of feeding-related nuclei of the brain. Endocrinology 149: 2062.

597-FTO|FTO Antibody抗体(Mouse monoclonal) phosphosolutions代理