Tocris/Desmethyl-YM 298198/2447/10/10 mg-蚂蚁淘生物

Description: Derivative of mGlu₁antagonist YM 298198 (Cat. No. 2448) Chemical Name: 6-Amino-N-cyclohexyl-3-methylthiazolo[3,2-a]benzimidazole-2-carboxamide hydrochloride Purity: ≥98% (HPLC) Biological Activity Technical Data Solubility Calculators DatasheetsReferences

Biological Activity

Derivative of the mGlu₁-selective antagonist YM 298198 (Cat. No. 2448).

Licensing Information

Sold with the permission of Astellas Pharma Inc.

Technical Data

M. Wt	364.89
Formula	C₁₇H₂₀N₄OS.HCl
Storage	Desiccate at RT
Purity	≥98% (HPLC)
CAS Number	1177767-57-5
PubChem ID	16759180
InChI Key	SWKZWXJQIDXGLX-UHFFFAOYSA-N
Smiles	Cl.CC1=C(SC2=NC3=CC=C(N)C=C3N12)C(=O)NC1CCCCC1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

All Tocris products are intended for laboratory research use only.

Solubility Data

Solvent Max Conc. mg/mL Max Conc. mM Solubility

DMSO

18.24

Preparing Stock Solutions

The following data is based on the product molecular weight 364.89. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg

1 mM	2.74 mL	13.7 mL	27.41 mL
5 mM	0.55 mL	2.74 mL	5.48 mL
10 mM	0.27 mL	1.37 mL	2.74 mL
50 mM	0.05 mL	0.27 mL	0.55 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution. Reconstitution Calculator

Reconstitution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Product Datasheets

Certificate of Analysis / Product Datasheet Safety Datasheet Select another language: English German French Spanish View SDS

References

References are publications that support the products\' biological activity.

Kohara et al (2005) Radioligand binding properties and pharmacological characterization of 6-Amino-N-cyclohexyl-N,3-dimethyl-thiazolo[3,2-a]-benzimidazole-2-carboxamide (YM-298198), a high-affinity, selective and noncompetitive antagonist of metabo J.Pharmacol.Exp.Ther. 315 163 PMID: 15976016

Keywords: Desmethyl-YM 298198, supplier, Derivative, mGlu1, mGluR1, antagonists, YM, 298198, Group, I, Receptors, Glutamate, Metabotropic, Desmethyl-YM298198, Glutamate, (Metabotropic), Group, I, Receptors, Glutamate, (Metabotropic), Group, I, Receptors, Tocris Bioscience