Potent, non-peptide and orally active oxytocin receptor antagonist (IC50 = 8.9 nM) that displays 40-fold selectivity over vasopressin V1a and V2 receptors (IC50 values are 370 and 570 nM respectively). Antagonizes oxytocin-induced uterine contractions in vitro and in vivo.
化合物库L-368,899 hydrochloride is also offered as part of the Tocriscreen 2.0 Max. 了解 Tocris 化合物库的更多信息。
CC(C=CC=C2)=C2N1CCN(S(CC34CCC(C(C)4C)C[C@@H]3NC([C@@H](N)CCS(C)(=O)=O)=O)(=O)=O)CC1.Cl上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
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以下数据基于产品分子量 591.23。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions. Molarity Calculator Calculate the mass, volume, or concentration required for a solution.*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).
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关键词: L-368,899 hydrochloride, L-368,899 hydrochloride supplier, Potent, non-peptide, oxytocin, receptor, antagonists, OT, Receptors, L368899, Oxytocin, 2641, Tocris Bioscience
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