- Description
- Product Info
- Shipping and Storage
- Downloads
- References
Description
GDC-0349 is an ATP-competitive inhibitor of mTOR that exhibits anticancer chemotherpeutic activity. GDC-0349 displays pre-clinical efficacy in vitro and in vivo.
Product Info
1207360-89-1 |
≥98% |
C24H32N6O3 |
452.55 |
1-ethyl-3-[4-[4-[(3S)-3-methylmorpholin-4-yl]-7-(oxetan-3-yl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-2-yl]phenyl]urea |
GDC0349 |
Tan to yellow solid |
Shipping and Storage
-20°C |
Ambient |
Downloads
G1310 Info Sheet PDF |
PI3K-Akt-mTORC Pathway Booklet |
References
Pei Z, Blackwood E, Liu L, et al. Discovery and Biological Profiling of Potent and Selective mTOR Inhibitor GDC-0349. ACS Med Chem Lett. 2012 Nov 29;4(1):103-7. PMID: 24900569.
