- Description
- Product Info
- Shipping and Storage
- Downloads
- References
Description
CX-6258 is an inhibitor of Pim kinase that exhibits anticancer chemotherapeutic activity. This compound decreases tumor growth in animal models of cancer.
Product Info
1202916-90-2 |
≥98% |
C26H24ClN3O3 |
461.95 |
(3E)-5-Chloro-3-[(5-{3-[(4-methyl-1,4-diazepan-1-yl)carbonyl]phenyl}-2-furyl)methylene]-1,3-dihydro-2H-indol-2-one |
Shipping and Storage
-20°C |
Ambient |
Downloads
C9200 Info Sheet PDF |
References
Padmanabhan A, Gosc EB, Bieberich CJ. Stabilization of the prostate-specific tumor suppressor NKX3.1 by the oncogenic protein kinase Pim-1 in prostate cancer cells. J Cell Biochem. 2013 May;114(5):1050-7. PMID: 23129228.
Haddach M, Michaux J, Schwaebe MK, et al. Discovery of CX-6258. A Potent, Selective, and Orally Efficacious pan-Pim Kinases Inhibitor. ACS Med Chem Lett. 2011 Dec 27;3(2):135-9. PMID: 24900437.
