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NEB/Histone H2B Human, Recombinant/M2505S/100 μg

Description:

Histone H2B combines with Histone H2A to form the H2A-H2B heterodimer. Two H2A/H2B heterodimers interact with an H3/H4 tetramer to form the histone octamer. Histone H2B is also modified by various enzymes and can act as a substrate for them. These modifications have been shown to be important in gene regulation.Protein Sequence: PEPAK SAPAP KKGSK KAVTK AQKKD GKKRK RSRKE SYSIY VYKVL KQVHP DTGIS SKAMG IMNSF VNDIF ERIAG EASRL AHYNK RSTIT SREIQ TAVRL LLPGE LAKHA VSEGT KAVTK YTSSK(Genbank accession number: AAN59961)

SDS-PAGE analysis of Histone H2B Human, Recombinant\"\"Lane 1: NEB Unstained Protein Marker, Broad Range (NEB #P7702), Lane 2-6: 0.5 μg, 1.0 μg, 2.0 μg, 5.0 μg, 10.0 μg Histone H2B Human, Recombinant. ESI-TOF Analysis of Histone H2B Human, Recombinant\"\"

Notes:

1 mg/ml, 73 µM is calculated using the molar extinction coefficient for Histone H2B (6400) and its absorbance at 280 nm (3,4). 1.0 A280 units = 2.2 mg/ml