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氢化可的松:Hydrocortisone | SIGMA-H0888 | BSZH | 北京北实纵横科技发展有限公司
别名11β,17α,21-三羟基孕甾-4-烯-3,20-二酮,17-羟基皮质甾酮,4-孕烯-11β,17α,21-三醇-3,20-二酮,氢化泼尼松龙,氢化皮质酮,皮质甾醇,氢化皮质素,可的索,17-Hydroxycorticosterone,Cortisol 级别细胞培养级 纯度 分析BioReagent, suitable for cell culture TipsBSZH品质推荐:SIGMA-ALDRICH 进口高等级试剂,多重遴选,国际标准严苛测试,全球生物化学产品质量标杆,满足用户更高应用要求。 使用SIGMA-ALDRICH品质优异、表现卓越的试剂类产品,将有助于使您的研究项目更早获益。 分子式C21H30O5 分子量362.46 储存条件常温避光保存。 性质

InChI Key JYGXADMDTFJGBT-VWUMJDOOSA-Nproduct line BioReagentassay 98%form powdermp 211-214 C(lit.)suitability suitable for cell culture

To prepare 50 g/mL stock solution, add 1.0 mL absolute ethanol to 1.0 mg of product, gently swirl to dissolve, add 19 mL sterile medium.

Physical form

室温下为粉末状;分成小份冻存,以避免使用时反复冷冻/解冻

Application

Hydrocortisone has been used as a supplement in culture media for oligodendrocytes, colon cells and epithelial cells.[3][4]

Biochem/physiol Actions

Hydrocortisone (also referred to as cortisol) is an endogenous glucocorticoid which is secreted by the adrenal gland. It is produced from the hypothalamus pituitary adrenal (HPA) axis. Hydrocortisone interacts with glucocorticoid receptors and regulates various signaling pathways. It is associated with the induction of energy mobilization, increase in cerebral perfusion rates and local glucose consumption. It is also linked with increase in cardiovascular output and respiration, redistribution of blood, delivery of molecules and energy to the brain and muscles and modulation of immune responses.[1][2]

肾上腺皮质分泌的原发性糖皮质激素。消炎效果是皮质酮的三倍,但 Na2+ 保留性能比皮质酮低。

警示性声明 P280个人防护装备 Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges危害码 (欧洲) Xn风险声明 (欧洲) 63安全声明 (欧洲) 36/37RIDADR NONH for all modes of transportWGK德国 3RTECS GM8925000