- Description
- Product Info
- Shipping and Storage
- Downloads
- References
Description
Nabumetone is a 1-naphthalenacetic acid derivative non-steroidal anti-inflammatory drug (NSAID) that inhibits COX-2. Nabumetone exhibits anti-inflammatory, analgesic, anticancer, and chemopreventive activities. In vivo, nabumetone inhibits intestinal carcinogenesis. In vitro, this compound induces apoptosis in colon cancer cells.
Product Info
42924-53-8 |
≥98% |
C15H16O2 |
228.29 |
4-(6-Methoxy-2-naphthalenyl)-2-butanone |
4-(6-methoxynaphthalen-2-yl)butan-2-one |
Arthaxan; Balmox; Consolan; Nabuser; Relafen; Relifen |
80°C |
Soluble in DMSO. Insoluble in water. |
White or almost white crystalline powder |
Shipping and Storage
Ambient |
Ambient |
Downloads
N0205 Info Sheet PDF |
References
Paul S, Das N, Ghosh S. The effects of aceclofenac and nabumetone in osteoarthritis. JNMA J Nepal Med Assoc. 2009 Apr-Jun;48(174):121-5. PMID: 20387351.
Roy HK, Karoski WJ, Ratashak A, et al. Chemoprevention of intestinal tumorigenesis by nabumetone: induction of apoptosis and Bcl-2 downregulation. Br J Cancer. 2001 May 18;84(10):1412-6. PMID: 11355956.
