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LC Labs/I-5577 Imatinib, Free Base, >99%/I-5577/1 g
  • This is the free base form of imatinib; please see the other form of this product, Imatinib, Methanesulfonate Salt, Cat. No. I-5508, for further technical information. The methanesulfonate salt form of imatinib is used for some or all imatinib formulation for use in humans.
  • Imatinib is the active ingredient in the drug product sold under the trade name Gleevec® and the other trade names listed above under \"Related Terms\". This drug has been approved in at least one country for use in patients with gastrointestinal stromal tumors, chronic myelogenous leukemia and a number of other malignancies. NOTE: THE IMATINIB, FREE BASE RESEARCH COMPOUND SOLD BY LC LABORATORIES IS NOT GLEEVEC® NOR ANY OTHER DRUG PRODUCT SPECIFIED BY THE TRADE NAMES LISTED ABOVE UNDER \"RELATED TERMS\", AND IS NOT FOR HUMAN USE.
  • NOTE: the trade names listed above under \"Related Terms\" are for imatinib-containing drug products and may apply variously to formulations of one or another form of imatinib, such as the free base, mesylate salt, or other forms.
  • This imatinib product is the free base, whose CAS number is given above. The CAS number of the methanesulfonate salt is 220127-57-1.
  • Sold for laboratory or manufacturing purposes only; not for human, medical, veterinary, food, or household use.
  • This product is offered for R&D use in accordance with (i) 35 USC 271(e)+A13(1) in the U.S.; (ii) Section 69.1 of Japanese Patent Law in Japan; (iii) Section 11, No. 2 of the German Patent Act of 1981 in Germany; (iv) Section 60, Paragraph 5b of the U.K. Patents Act of 1977 in the U.K.; (v) Sections 55.2(1) and 55.2(6) and other common law exemptions of Canadian patent law; (vi) Section 68B of the Patents Act of 1953 in New Zealand together with the amendment of same by the Statutes Amendment Bill of 2002; (vii) such related legislation and/or case law as may be or become applicable in the aforementioned countries; and (viii) such similar laws and rules as may apply in various other countries.
  • Not available in some countries; not available to some institutions; not available for some uses.

Related Terms:

[Glamox] [Gleevec] [Glivec] [Genfatinib]M.W. 493.60C29H31N7O[152459-95-5]M.I. 14: 4902

Storage

Store at or below -20 ºC

Solubility

Soluble in DMSO at 25 mg/mL with slight warming; soluble in ethanol at 5 mg/mL with slight warming; very poorly soluble in water; maximum solubility in plain water is estimated to be about 5-20 µM; buffers, serum, or other additives may increase or decrea

Disposal

A