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LifeSensors/4110-1,000UNITS SUMOstar Protease/4110-1,000UNITS SUMOstar Protease

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4110-1,000UNITSSUMOstarProtease

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Life Sensors

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Recombinant SUMOstar Protease 1 specifically recognizes and cleaves the SUMOstar tag from recombinant fusion proteins made with SUMOstar expression systems (Cat.#s: 1100A, 1106, 1100K, 1101, 2100, 2101, 2160, 2161, 3100, 3101, 7110, 7111, 7120, 7121). Unlike thrombin, EK, or TEV proteases, which recognize short, linear sequences, SUMOstar Protease 1 recognizes the tertiary structure of SUMOstar. As a result, SUMOstar Protease 1 will not cleave within the protein of interest. SUMOstar Protease 1 will not cleave SUMO-tags from proteins expressed with the SUMOpro or SUMOpro3 systems. To cleave the SUMOpro tag (orginial yeast SUMO tag), please use SUMO Protease 1 and to cleave SUMOpro3 tag please use SUMO Protease 2.By purchasing this product, the purchaser agrees to comply with the terms of our Limited Use Label License.Need bulk quantities? We would be happy to work out a custom price that fits your budget. Please click here to request a quote.InfoMolecular weight26 kDaFusion tagHis6SourceE. coliPurity>95%Physical stateLiquidActivity>105 Unit/mg1U of SUMOstar Protease 1 cleaves >90% of 100 ug SUMOstar Protease 1 Control Protein in 1 hour (30°C)Storage/StabilityStore at -80°C, avoiding repeated freeze-thaw cycles. Stable for up to one year under these conditions.ApplicationsSUMOstar Protease 1 contains a polyhistidine tag at the N-terminus, allowing easy removal from the cleavage reaction by affinity chromatography. The protease cleaves consistently over a broad range of temperature (30°C is optimal), pH [5.5-9.5], and ionic strength.Specifically engineered to recognize and cleave the SUMOstar fusion tagDocumentsDatasheetLimited use of Label License

LifeSensors公司目前主要的产品有400多种，其产品主要覆盖泛素和泛素蛋白酶体通路等科学应用领域，并且产品线在不断的扩大中。公司开创了两大独家技术平台：用于细胞信号和药物发现的泛素蛋白酶体系统(UPS)，以及增强目的蛋白在大肠杆菌、酵母、昆虫和哺乳动物细胞中表达与纯化的SUMO融合表达系统。

泛素蛋白酶体系统正在成为继激酶之后，药物发现的下一个机遇，必将成为未来许多新型药物的创新来源。作为泛素蛋白领域的先驱公司，药物的发现、分析化合物以及去泛素酶和泛素化酶的高通量筛选正是LifeSensors创新技术的真正亮点。此外，LifeSensors还为泛素的蛋白质组学提供众多定制技术服务，并且已经开发了各种各样的测定细胞中的生理底物或生物标志物的方法。