product data sheet

Catalog No.: 56217

Size: 100 ug in 10 mM PBS, pH 7.4.

SMRT (Silencing Mediator for Retinoid and Thyroid receptors) is a 168 kD nuclear protein. Nuclear hormone receptors are transcription factors regulated by ligand binding. In the absence of ligand, there is a physical interaction between the nuclear receptors that do not interact with Hsp90 and a family of corepressors which includes SMRT. SMRT helps target histone deacetylases and other components of a multiprotein repressor complex to the specific target promoter to silence gene transcription.

Antigen: A KLH-conjugated synthetic peptide derived from human SMRT corresponding to aa 994-1005

Host Species: Mouse Stabilizers: None Preservatives: None. Available on request.

This antibody recognizes human SMRT.

Immunoblotting and Immuno- precipitation: use at 1-5 ug/ml.

Positive control: HBL100

Dilute in PBS or medium which is identical to that used in the assay system.

This antibody is stable for at least one

(1) year at -20oC. Avoid multiple freeze- thaw cycles.

For in vitro investigational use only. Not for use in therapeutic or diagnostic procedures.

QED Bioscience, Inc. 10919 Technology Place, Suite C

San Diego, CA 92127

Toll Free 800.929.2114

Phone 858.675.2405

Fax 858.592.1509

info@qedbio.com

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