Adipogen/FasL, Soluble (human) (rec.)/AG-40B-0001-3010/3 x 10 µg
More Information Product Details
Synonyms | APO-1L; CD95L; CD178; TNFSF6; Fas Ligand |
Product Type | Protein |
Properties
Source/Host | HEK 293 cells |
Sequence | The extracellular domain of human FasL (aa 103-281) is fused at the N-terminus to a FLAG®-tag. |
Crossreactivity | HumanMouse |
Biological Activity | Induces apoptosis of human Jurkat T cells at a concentration of <1ng/ml in the presence of 0.1 to 1μg/ml TNF Ligands Enhancer (Prod. No. AG-35B-0001). In the absence of TNF Ligands Enhancer, FasL is working at 50-100 fold higher concentrations. |
MW | ~33kDa (SDS-PAGE) |
Purity | ≥95% (SDS-PAGE) |
Endotoxin Content | |
Concentration | 0.1mg/ml after reconstitution. |
Reconstitution | Reconstitute with 100μl sterile water. |
Formulation | Lyophilized. Contains PBS. |
Other Product Data | UniProt link P48023: FasL (human) FLAG is a registered trademark of Sigma-Aldrich Co. |
Shipping and Handling
Shipping | BLUE ICE |
Short Term Storage | +4°C |
Long Term Storage | -20°C |
Handling Advice | After reconstitution, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.PBS containing at least 0.1% BSA should be used for further dilutions. |
Use/Stability | Stable for at least 6 months after receipt when stored at -20°C. |
Documents
MSDS ![](\"https://www.ebiomall.com/images/adipogen/download.png\") Download PDF |
Product Specification Sheet
Datasheet | Download PDF |
FasL is a cytokine that binds to TNFRSF6/Fas, a receptor that transduces the apoptotic signal into cells. Is involved in cytotoxic T cell mediated apoptosis and in T cell development.
