Fitzgerald/LGALS3BP antibody/10R-4627/100 ul
OVERVIEW:
Synonyms | Monoclonal LGALS3BP antibody, Anti-LGALS3BP antibody, Lectin Galactoside-Binding Soluble 3 Binding Protein antibody, 90K antibody, MAC-2-BP antibody, LGALS3BP, LGALSBP 3, LGALSBP-3, LGALSBP 3 antibody, LGALSBP-3 antibody |
Cross Reactivity | Human |
Applications | FC, IF, IHC, WB |
Immunogen | LGALS3BP antibody was raised in mouse using a human recombinant protein fragment corresponding to amino acids 19-300 of human LGALS3BP (NP_005558) produced in E. coli as the immunogen. |
SPECIFICATIONS:
Host | Mouse |
Clone | 3G8 |
Isotype | IgG1 |
Method of Purification | LGALS3BP antibody was purified by affinity chromatography. |
Form & Buffer | Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide. |
Concentration | 500 ug-1 mg/ml |
STORAGE & SAFETY:
Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
Usage Assay Information:
Usage Recommendations | FC: 1:100, IF: 1:100, IHC: 1:150, WB: 1:500 |
GENERAL INFORMATION:
Biological Significance | The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1. |
