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Fitzgerald/EIF2B3 antibody/10R-3946/100 ul

OVERVIEW:

Synonyms Cross Reactivity Applications Immunogen
Monoclonal EIF2B3 antibody, Anti-EIF2B3 antibody, Eukaryotic translation initiation factor 2B subunit 3 gamma antibody, EIF-2B antibody, EIF2Bgamma antibody, Translation initiation factor eIF-2B subunit gamma antibody, EIF2B3, EIFB3 2, EIFB3-2, EIFB3 2 antibody, EIFB3-2 antibody
Human
IF, WB
EIF2B3 antibody was raised in mouse using a full length recombinant protein of human EIF2B3 (NP_065098) produced in HEK293T cells, as the immunogen.

SPECIFICATIONS:

Host Clone Isotype Method of Purification Form & Buffer Concentration
Mouse
2H1
IgG1
EIF2B3 antibody was purified by affinity chromatography.
Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
500 ug-1 mg/ml

STORAGE & SAFETY:

Storage
Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

Usage Assay Information:

Usage Recommendations
IF: 1:100, WB: 1:2000

GENERAL INFORMATION:

Biological Significance
EIF2B3 is one of the subunits of initiation factor eIF2B, which catalyzes the exchange ofeukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis Cvirus internal ribosome entry site-mediated translation. Mutations in this gene have been associated withleukodystrophy with vanishing white matter.