首页 > NSJ Bio > NSJ Bio/TMEPAI Antibody / PMEPA1 [clone PMEPA1/2696] (V7336)/100 ug/V7336-100UG

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NSJ Bio/TMEPAI Antibody / PMEPA1 [clone PMEPA1/2696] (V7336)/100 ug/V7336-100UG

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V7336-100UG

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NSJ Bio

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DescriptionPMEPA1 (prostate transmembrane protein, androgen induced 1), or TMEPAI (Transmembrane prostate androgen induced protein) is a 287 amino acid single-pass membrane protein that contains WW-binding motifs and localizes to the cell membrane. Expressed at high levels in prostate, kidney and ovary, PMEPA1/TMEPAI interacts with NEDD4 and may play a role in regulating AR (androgen receptor) levels, specifically in prostate cells. Down regulation of TMEPAI is observed in prostate tumors, suggesting that TMEPAI may exhibit activity as a tumor suppressor. Overexpression of this protein may play a role in multiple types of cancer.Application NotesOptimal dilution of the TMEPAI antibody should be determined by the researcher.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.ImmunogenFull-length recombinant human protein was used as the immunogen for the TMEPAI antibody.StorageStore the TMEPAI antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).Related Products1. View all TMEPAI antibodies

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